从日本和泉平原分离出的一株禽H4N6流感病毒的基因特征分析。
Genetic characterization of an avian H4N6 influenza virus isolated from the Izumi plain, Japan.
作者信息
Okuya Kosuke, Kanazawa Norihiro, Kanda Takehiro, Kuwahara Masakazu, Matsuu Aya, Horie Masayuki, Masatani Tatsunori, Toda Shigehisa, Ozawa Makoto
机构信息
Joint Faculty of Veterinary Medicine, Laboratory of Animal Hygiene, Kagoshima University, Kagoshima, Kagoshima 890-0065, Japan.
Matsuoka Research Institute for Science, Tokyo 184-0003 , Japan.
出版信息
Microbiol Immunol. 2017 Nov;61(11):513-518. doi: 10.1111/1348-0421.12545.
An influenza A virus of H4N6 subtype was isolated from the Izumi plain, Japan, in 2013. Genetic analyses revealed that two viral genes (M and NS gene segments) of this isolate were genetically distinct from those of the H4N6 virus isolated from the same place in 2012. Furthermore, three viral genes (PB2, PB1 and M gene segments) of this isolate share high similarity with those of the North American isolates of 2014. These results suggest a high frequency of genetic reassortment of avian influenza viruses in Asian waterfowl and intercontinental movements of avian influenza viruses via migratory waterfowl.
2013年，从日本和泉平原分离出一株H4N6亚型甲型流感病毒。基因分析显示，该分离株的两个病毒基因（M基因片段和NS基因片段）在基因上与2012年从同一地点分离出的H4N6病毒不同。此外，该分离株的三个病毒基因（PB2基因片段、PB1基因片段和M基因片段）与2014年北美分离株的基因高度相似。这些结果表明，禽流感病毒在亚洲水禽中基因重配的频率很高，并且禽流感病毒通过迁徙水禽进行洲际传播。
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