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[雌激素诱导多种肝脏酶活性增加的发展及意义]

[Development and significance of estrogen-induced increase in the activity of several liver enzymes].

作者信息

Németh S

机构信息

Institut für experimentelle Endokrinologie, Bratislava/CSSR.

出版信息

Z Gesamte Inn Med. 1988 Aug 1;43(15):418-20.

PMID:2902713
Abstract

In experiments on adult, female rats, the author confirm the stimulatory effect of 50 micrograms kg-1 17-beta-estradiol daily, s.c., for more than 1 week on the activity of liver tyrosine aminotransferase and tryptophan pyrrolase and describe experiments suggesting an increased glucocorticoid sensitivity, as a consequence of the estrogen treatment. The study contributes to the information on potential side effects of hormonal contraception.

摘要

在对成年雌性大鼠进行的实验中,作者证实,每天皮下注射50微克/千克的17-β-雌二醇,持续1周以上,可刺激肝脏酪氨酸转氨酶和色氨酸吡咯酶的活性,并描述了一些实验,这些实验表明雌激素治疗会导致糖皮质激素敏感性增加。该研究有助于了解激素避孕的潜在副作用。

相似文献

1
[Development and significance of estrogen-induced increase in the activity of several liver enzymes].[雌激素诱导多种肝脏酶活性增加的发展及意义]
Z Gesamte Inn Med. 1988 Aug 1;43(15):418-20.
2
Interaction of glucocorticoids in stimulation of liver tyrosine aminotransferase and tryptophan pyrrolase by estrogen in female rats.雌性大鼠中糖皮质激素在雌激素刺激肝脏酪氨酸转氨酶和色氨酸吡咯酶过程中的相互作用。
Endocrinol Exp. 1984 Dec;18(4):215-21.
3
Basal and glucocorticoid induced changes of hepatic glucocorticoid receptor during aging: relation to activities of tyrosine aminotransferase and tryptophan oxygenase.衰老过程中基础及糖皮质激素诱导的肝脏糖皮质激素受体变化:与酪氨酸转氨酶和色氨酸加氧酶活性的关系
Biogerontology. 2005;6(2):113-31. doi: 10.1007/s10522-005-3498-y.
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The effect of stress on the activity of hepatic tryptophan pyrrolase, of tyrosine aminotransferase in various organs and on the level of tryptophan in the liver and plasma of rats.应激对大鼠肝脏色氨酸吡咯酶活性、各器官酪氨酸转氨酶活性以及肝脏和血浆中色氨酸水平的影响。
Physiol Bohemoslov. 1977;26(6):557-63.
5
Inhibitory effect of immobilization stress on depression of liver tyrosine aminotransferase and tryptophan pyrrolase by glucose feeding in rats.制动应激对葡萄糖喂养大鼠肝脏酪氨酸转氨酶和色氨酸吡咯酶活性降低的抑制作用
Endocrinol Exp. 1977 Mar;11(1):43-8.
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Adrenal hormones and increase of liver tyrosine aminotransferase and tryptophan pyrrolase activity after immobilization in rats.大鼠固定后肾上腺激素及肝脏酪氨酸转氨酶和色氨酸吡咯酶活性的增加
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Effect of halopredone acetate on rat liver tryptophan oxygenase and tyrosine aminotransferase activities.
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Effects of nafoxidine and oestriol on the oestradiol-induced activation of rat liver tryptophan oxygenase and tyrosine aminotransferase and increase in uterine weight.萘福昔定和雌三醇对雌二醇诱导的大鼠肝脏色氨酸加氧酶和酪氨酸转氨酶激活以及子宫重量增加的影响。
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[Activity of various liver enzymes in rats following a flight aboard the Cosmos-936 biosatellite].[大鼠搭乘宇宙-936生物卫星飞行后各种肝酶的活性]
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