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狂犬病暴露后预防数据的描述性分析:2013年,加拿大安大略省

A descriptive analysis of rabies post-exposure prophylaxis data: 2013, Ontario, Canada.

作者信息

Middleton D, Edwin J J, Johnson K O, Warshawsky B F

机构信息

Public Health Ontario, Toronto, ON, Canada.

Centre for Public Health Infrastructure, Public Health Agency of Canada, Ottawa, ON, Canada.

出版信息

Zoonoses Public Health. 2018 Feb;65(1):e66-e78. doi: 10.1111/zph.12410. Epub 2017 Oct 13.

Abstract

By 2013, the number of confirmed rabid animals in Ontario had decreased to unprecedented low numbers, yet the expected decrease in the number of courses of rabies post-exposure prophylaxis (RPEP) administered did not occur consistent with the decrease in animal rabies cases (Figure ). This prompted a review of the reasons that RPEP was administered in Ontario. This study provides a descriptive analysis of the exposure incidents resulting in RPEP administration in Ontario during 2013 using data obtained from the integrated Public Health Information System, a Web-based disease surveillance system. Findings from the study revealed that the number of RPEP courses administered could be reduced, without increased risk of rabies, through the following strategies: (i) Education and resources for public health staff and healthcare providers who assess animal exposures to improve interpretation of guidelines for RPEP administration. (ii) Refinement of guidelines for public health staff and healthcare providers to ensure that they support detailed consideration of the circumstances of the exposure in order to assist with the risk assessment. Guidelines should also support completion of a risk assessment when exposures to skunks, foxes, raccoons and other wild carnivores are provoked by the victim, as opposed to automatically providing RPEP as recommended by current guidelines. (iii) Public education strategies to prevent exposures to animals (e.g., do not touch unattended animals, bat proofing your house, proper removal of bats from the house). (iv) Defining the criteria to declare a jurisdiction rabies-free. (v) Exploring strategies to improve surveillance for rabid animals.

摘要

到2013年,安大略省确诊的狂犬病动物数量已降至前所未有的低水平,然而,狂犬病暴露后预防(RPEP)疗程数量的预期减少并未与动物狂犬病病例的减少相一致(图)。这促使对安大略省实施RPEP的原因进行审查。本研究利用从基于网络的疾病监测系统——综合公共卫生信息系统获得的数据,对2013年安大略省导致实施RPEP的暴露事件进行了描述性分析。该研究的结果表明,通过以下策略可以减少RPEP疗程的数量,同时不增加狂犬病风险:(i)为评估动物暴露情况的公共卫生工作人员和医疗服务提供者提供教育和资源,以改善对RPEP实施指南的解读。(ii)完善公共卫生工作人员和医疗服务提供者的指南,以确保这些指南支持对暴露情况进行详细考虑,以协助进行风险评估。当受害者激怒臭鼬、狐狸、浣熊和其他野生食肉动物导致暴露时,指南还应支持完成风险评估,而不是像当前指南所建议的那样自动提供RPEP。(iii)开展公共教育策略,以防止接触动物(例如,不要触摸无人看管的动物,对房屋进行防蝙蝠处理,正确清除房屋内的蝙蝠)。(iv)确定宣布一个管辖区无狂犬病的标准。(v)探索改善狂犬病动物监测的策略。

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