Institute of Population Research, Peking University, Beijing, China.
Institute of Population Research, Peking University, Beijing, China; WHO Collaborating Center on Reproductive Health and Population Science, Beijing, China.
Psychiatry Res. 2018 Jan;259:27-31. doi: 10.1016/j.psychres.2017.08.046. Epub 2017 Aug 31.
There is limited evidence on the association between socioeconomic status (SES) and autism in developing nations. The aim of this study was to examine this association among children aged 0-17 years in China. We obtained data from the Second National Sample Survey on Disability, and selected 616,940 children for analysis. Autism was ascertained according to the International Statistical Classification of Diseases, Tenth Revision. Multiple logistic regressions allowing for weights showed that children in middle-income and high-income families were less likely than their low-income peers to have autism, with an odds ratio of 0.60 (95%CI: 0.39, 0.93) and 0.44 (95%CI: 0.27, 0.72), respectively. Children in middle-education families had 63% (95%CI: 41%, 95%) odds of autism relative to their counterparts in low-education families. Stratified analyses found that all observed associations were only in male children, not in female children. In conclusion, children in families with socioeconomic disadvantage, in the form of lower family income and education, had greater risk of childhood autism.
关于社会经济地位(SES)与发展中国家自闭症之间的关联,证据有限。本研究的目的是在中国 0-17 岁儿童中检验这种关联。我们从第二次全国残疾人抽样调查中获取了数据,并选择了 616940 名儿童进行分析。自闭症是根据国际疾病分类第十版确定的。允许加权的多因素逻辑回归显示,中高收入家庭的儿童患自闭症的可能性低于低收入家庭的儿童,其优势比分别为 0.60(95%CI:0.39,0.93)和 0.44(95%CI:0.27,0.72)。中等教育家庭的儿童患自闭症的几率比低教育家庭的儿童高 63%(95%CI:41%,95%)。分层分析发现,所有观察到的关联仅见于男性儿童,而不是女性儿童。总之,社会经济地位处于劣势的家庭,即家庭收入和教育水平较低的家庭,其儿童患自闭症的风险更高。