Fernández Epifanio J L, García-Miguel P, Ruíz Villaespesa A, Muñóz Villa A
An Esp Pediatr. 1979 Jun-Jul;12(6-7):523-8.
Two cases of childhood leukemia with hypercalcemia are reported. In the first case who died by acute granulocytic leukemia, autopsy showed a generalized calcinosis. The other case was an acute lymphocitic leukemia with hypercalcemia and destructive lessions of bones with pathologic fractures. Response to chemotherapy was good. Literature about mechanismes which can induce hypercalcemia in malignancy is reviewed.
报告了两例儿童白血病伴高钙血症的病例。第一例死于急性粒细胞白血病,尸检显示全身钙质沉着。另一例是急性淋巴细胞白血病伴高钙血症及骨骼破坏性病变并伴有病理性骨折。化疗反应良好。本文综述了关于恶性肿瘤中可诱发高钙血症机制的文献。