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腹主动脉瘤修复术后的生存差异凸显了种族和社会经济地位的不平等。

Survival Disparity Following Abdominal Aortic Aneurysm Repair Highlights Inequality in Ethnic and Socio-economic Status.

机构信息

Department of Surgery, University of Otago, Christchurch, New Zealand.

Maori/Indigenous Health Institute, University of Otago, Christchurch, New Zealand.

出版信息

Eur J Vasc Endovasc Surg. 2017 Dec;54(6):689-696. doi: 10.1016/j.ejvs.2017.08.018. Epub 2017 Oct 10.

Abstract

OBJECTIVES

Socio-economic status (SES) and ethnicity have been reported as markers influencing the likelihood of increased mortality. The aim of this study was to investigate how SES and ethnicity impacted patient survival after abdominal aortic aneurysm (AAA) repair.

METHODS

Consecutive patients undergoing open and endovascular AAA repair during a 14.5 year period were identified. Ethnicity was defined as recorded on health records and SES (a score of 10, where 1 is least deprived and 10 being most deprived) and was linked to census data. Operative outcomes were reported at 30 days and a medium-term survival analysis used the Cox model to report adjusted hazard ratios (HR).

RESULTS

A total of 6239 patients with a median age of 75 years and 78.7% males were included. The majority (5,654) were identified as New Zealand (NZ) Europeans, with 421 identified as NZ Maori, 97 identified as belonging to a Pacific ethnic group, and 67 identified as an Asian ethnic group. The median survival follow-up period was 5 years and after adjusting for confounders, those who identified as NZ Maori had the lowest survival compared with all other ethnic groups with a HR of 1.46 (95% CI 1.23-1.72). Living in areas of high social deprivation ≥ 7 was an independent predictor of short and medium-term overall mortality when compared with living in deprivation deciles 1 or 2.

CONCLUSIONS

Low SES was identified as a marker of risk for all ethnic groups in relation to both reduced short and medium-term survival. However, regardless of SES, NZ Maori had worse overall medium-term survival following AAA repair than the other ethnic groups. Therefore it appears that both SES and being Maori were markers of increased exposure to risk that negatively impact upon survival after AAA repair. There is a need to ensure systemic processes support initiatives that reduce this inequality.

摘要

目的

社会经济地位(SES)和种族已被报道为影响死亡率增加的标志物。本研究旨在探讨 SES 和种族如何影响腹主动脉瘤(AAA)修复后的患者生存。

方法

确定了 14.5 年期间接受开放和血管内 AAA 修复的连续患者。种族定义为健康记录中记录的种族,SES(评分 10,其中 1 是最不贫困,10 是最贫困),并与人口普查数据相关联。报告了 30 天的手术结果,并使用 Cox 模型报告了调整后的危险比(HR)进行中期生存分析。

结果

共纳入了 6239 名中位年龄为 75 岁且 78.7%为男性的患者。大多数(5654 人)被确定为新西兰(NZ)欧洲人,421 人被确定为新西兰毛利人,97 人被确定为太平洋种族群体,67 人被确定为亚洲种族群体。中位随访期为 5 年,在调整混杂因素后,与其他所有种族相比,新西兰毛利人被认为是生存率最低的,其 HR 为 1.46(95%CI 1.23-1.72)。与生活在贫困程度最低的 1 或 2 个贫困阶层相比,生活在贫困程度≥7 的高社会剥夺地区是短期和中期总体死亡率的独立预测因素。

结论

SES 低被确定为所有种族的风险标志物,与短期和中期生存率降低有关。然而,无论 SES 如何,新西兰毛利人在接受 AAA 修复后,整体中期生存率均较差,与其他种族相比。因此,似乎 SES 和毛利人都是增加风险暴露的标志物,这对 AAA 修复后的生存产生了负面影响。需要确保系统流程支持减少这种不平等的举措。

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