Laboratory of Neuroimmunology, C. Mondino National Neurological Institute, Via Mondino 2, I-27100, Pavia, Italy.
C. Mondino National Neurological Institute, University of Pavia, Pavia, Italy.
Neurol Sci. 2017 Oct;38(Suppl 2):231-236. doi: 10.1007/s10072-017-3027-1.
This document presents the guidelines for anti-aquaporin-4 (AQP4) antibody testing that has been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on neuromyelitis optica spectrum disorders, indications and limits of anti-AQP4 antibody testing, instructions for result interpretation, and an agreed laboratory protocol (Appendix) are reported for the communicative community of neurologists and clinical pathologists.
本文件介绍了抗水通道蛋白-4（AQP4）抗体检测的指南，该指南是在基于问卷调查、互联网联系以及赞助的意大利神经免疫学会（AINI）大会研讨会讨论的共识过程中制定的。关于视神经脊髓炎谱系疾病的基本临床信息、抗 AQP4 抗体检测的适应证和限制、结果解释说明以及已达成一致的实验室方案（附录）都报告给了神经科医生和临床病理学家的交流社区。
