人类免疫缺陷病毒感染后克罗恩病的缓解
Remission of Crohn's disease after human immunodeficiency virus infection.
作者信息
James S P
机构信息
Mucosal Immunity Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
出版信息
Gastroenterology. 1988 Dec;95(6):1667-9. doi: 10.1016/s0016-5085(88)80094-5.
PMID:2903112
Abstract
A patient with an 18-yr history of Crohn's disease of the colon became infected with the human immunodeficiency virus. The patient had a complete remission of gastrointestinal symptoms in association with progressive immunodeficiency. This finding suggests that CD4 T cells and an intact immune response play a central role in the pathogenesis of Crohn's disease.
摘要
一名患有18年结肠克罗恩病病史的患者感染了人类免疫缺陷病毒。该患者随着免疫缺陷的进展，胃肠道症状完全缓解。这一发现表明，CD4 T细胞和完整的免疫反应在克罗恩病的发病机制中起核心作用。
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