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头皮斑块型蓝色痣伴皮下细胞结节的黑素瘤。

Melanoma arising from a plaque-type blue naevus with subcutaneous cellular nodules of the scalp.

机构信息

Department of Dermatology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Section of Dermatology, Department of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.

出版信息

Clin Exp Dermatol. 2018 Mar;43(2):164-167. doi: 10.1111/ced.13287. Epub 2017 Oct 15.

Abstract

Plaque-type blue naevus (PTBN) is a very rare variant of blue naevus (BN). The potential malignancy of subcutaneous cellular nodules (SCN) in PTBN was discovered in 2012, and there is currently no clear consensus on prognostic factors or management guidelines of such lesions. PTBN on the scalp have not been described in the literature. We report the clinical, histopathological and immunohistological features of a 50-year-old man who presented with a 30-year history of scalp PTBN, with malignant proliferation of nodular elements and fatal outcome 8 years later. This case suggests that long-term monitoring of patients with PTBN is required. Early surgical removal of such lesions should be considered, especially in the presence of any case of enlargement or change.

摘要

斑块型蓝色痣(PTBN)是蓝色痣(BN)的一种非常罕见的变体。2012 年发现 PTBN 中的皮下细胞结节(SCN)具有潜在的恶性,目前对于这些病变的预后因素或管理指南尚无明确共识。头皮上的 PTBN 在文献中尚未描述。我们报告了一名 50 岁男性的临床、组织病理学和免疫组织化学特征,该患者 30 年前头皮出现 PTBN,结节性成分出现恶性增殖,8 年后死亡。该病例提示需要对 PTBN 患者进行长期监测。对于此类病变,应考虑早期手术切除,特别是在有任何增大或变化的情况下。

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