Jha Abhijeet K, Prasad Smita, Sinha Rajesh
Department of Skin & V.D, Patna Medical College & Hospital, Patna, India.
Department of Dermatology, All India Institute of medical sciences, Patna, India.
J Cosmet Dermatol. 2018 Jun;17(3):437-440. doi: 10.1111/jocd.12443. Epub 2017 Oct 15.
Vitiligo is one of the commonest pigmentary disorders characterized by destruction of melanocytes.
To evaluate the efficacy of topical bimatoprost ophthalmic solution in stable facial vitiligo.
Eight cases of stable facial vitiligo were treated with bimatoprost 0.03% ophthalmic solution once daily for 12 weeks. Photographic records were taken at 2 weeks follow-up along with dermoscopic (Polarized, 10×) evaluation.
Four cases had excellent repigmentation, two cases had partial repigmentation and two cases had poor response.
Bimatoprost seems to be promising in treating stable vitiligo but large-scale studies are required.
白癜风是最常见的色素沉着障碍之一,其特征是黑素细胞遭到破坏。
评估局部使用比马前列素滴眼液治疗稳定期面部白癜风的疗效。
8例稳定期面部白癜风患者使用0.03%比马前列素滴眼液,每日一次,共治疗12周。在随访2周时进行摄影记录,并进行皮肤镜(偏振光,10倍)评估。
4例患者色素沉着良好,2例部分色素沉着,2例反应不佳。
比马前列素在治疗稳定期白癜风方面似乎有前景,但需要大规模研究。