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比马前列素眼药水治疗面部白癜风

Bimatoprost ophthalmic solution in facial vitiligo.

作者信息

Jha Abhijeet K, Prasad Smita, Sinha Rajesh

机构信息

Department of Skin & V.D, Patna Medical College & Hospital, Patna, India.

Department of Dermatology, All India Institute of medical sciences, Patna, India.

出版信息

J Cosmet Dermatol. 2018 Jun;17(3):437-440. doi: 10.1111/jocd.12443. Epub 2017 Oct 15.

Abstract

BACKGROUND

Vitiligo is one of the commonest pigmentary disorders characterized by destruction of melanocytes.

AIM

To evaluate the efficacy of topical bimatoprost ophthalmic solution in stable facial vitiligo.

MATERIAL AND METHODS

Eight cases of stable facial vitiligo were treated with bimatoprost 0.03% ophthalmic solution once daily for 12 weeks. Photographic records were taken at 2 weeks follow-up along with dermoscopic (Polarized, 10×) evaluation.

RESULTS

Four cases had excellent repigmentation, two cases had partial repigmentation and two cases had poor response.

CONCLUSION

Bimatoprost seems to be promising in treating stable vitiligo but large-scale studies are required.

摘要

背景

白癜风是最常见的色素沉着障碍之一,其特征是黑素细胞遭到破坏。

目的

评估局部使用比马前列素滴眼液治疗稳定期面部白癜风的疗效。

材料与方法

8例稳定期面部白癜风患者使用0.03%比马前列素滴眼液,每日一次,共治疗12周。在随访2周时进行摄影记录,并进行皮肤镜(偏振光,10倍)评估。

结果

4例患者色素沉着良好,2例部分色素沉着,2例反应不佳。

结论

比马前列素在治疗稳定期白癜风方面似乎有前景,但需要大规模研究。

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