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美国儿童疑似胆囊运动障碍性胆囊切除术的趋势

Trends of Cholecystectomies for Presumed Biliary Dyskinesia in Children in the United States.

作者信息

Matta Sravan R, Kovacic Katja, Yan Ke, Simpson Pippa, Sood Manu R

机构信息

Division of Pediatric Gastroenterology, Hepatology and Nutrition.

Division of Quantitative Health Sciences, Medical College of Wisconsin, Milwaukee, WI.

出版信息

J Pediatr Gastroenterol Nutr. 2018 May;66(5):808-810. doi: 10.1097/MPG.0000000000001777.

Abstract

BACKGROUND

Biliary dyskinesia (BD) is a controversial clinical entity. Standardized diagnostic test and management guidelines are lacking in children. Published data suggest that long-term outcomes of surgical and medical management are similar. We sought to determine national population-based trends of cholecystectomies performed in children for BD and associated healthcare expenditure in the United States during a 10-year period.

METHODS

Using Nationwide Inpatient Sample and the International Classification of Diseases, the 9th revision clinical modification codes, we identified children who had a cholecystectomy for BD from 2002 to 2011 in the United States.

RESULTS

A total of 66,380 cholecystectomies were identified as primary procedural diagnosis using weighted analysis from 2002 to 2011 in children. BD was the primary indication for cholecystectomy in 6674 (10.8%) of the patients. During the study period, the number of cholecystectomies performed for BD in children increased from 6.6% in 2002 to 10.6% in 2011, and a majority were adolescent white females. The annual health care expenditure for surgical management of BD for children in the US was estimated to almost $16 million/year.

CONCLUSIONS

Despite lack of standardized diagnostic criteria and variable outcomes of surgical intervention reported in pediatric literature, cholecystectomies are commonly performed for children with BD in the United States. Consensus guidelines for the diagnosis and management of this controversial disorder in children are needed.

摘要

背景

胆囊运动障碍(BD)是一个存在争议的临床实体。儿童缺乏标准化的诊断测试和管理指南。已发表的数据表明,手术和药物治疗的长期结果相似。我们试图确定美国10年间儿童因BD进行胆囊切除术的全国人群趋势以及相关的医疗保健支出。

方法

使用全国住院患者样本和国际疾病分类第九版临床修订版编码,我们确定了2002年至2011年在美国因BD进行胆囊切除术的儿童。

结果

通过对2002年至2011年儿童进行加权分析,共确定66380例胆囊切除术为主要手术诊断。BD是6674例(10.8%)患者胆囊切除术的主要指征。在研究期间,儿童因BD进行胆囊切除术的数量从2002年的6.6%增加到2011年的10.6%,大多数是青春期白人女性。美国儿童BD手术治疗的年度医疗保健支出估计约为每年1600万美元。

结论

尽管儿科文献报道缺乏标准化诊断标准且手术干预结果不一,但在美国,胆囊切除术仍是BD患儿常见的手术。需要针对这种有争议的儿童疾病制定诊断和管理的共识指南。

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