维莫非尼治疗肺腺癌继发环状肉芽肿
Granuloma Annulare Secondary to Vemurafenib Therapy for Lung Adenocarcinoma.
作者信息
Jenkinson Helena A, Siroy Alan E, Choksi Adrienne
出版信息
J Drugs Dermatol. 2017 Oct 1;16(10):1050-1052.
Numerous cutaneous manifestations have been associated with use of BRAF inhibitors, including two previously reported cases of granuloma annulare (GA) eruptions associated with vemurafenib therapy. Both of these patients were being treated for metastatic melanoma. In this report, we describe the case of a 71-year-old man who developed classic GA lesions while being treated with vemurafenib monotherapy for nonmelanoma cancer, specifically metastatic lung adenocarcinoma positive for BRAF V600 mutation.
J Drugs Dermatol. 2017;16(10):1050-1052.
.使用BRAF抑制剂已出现多种皮肤表现，包括先前报道的两例与维莫非尼治疗相关的环状肉芽肿（GA）皮疹。这两名患者均在接受转移性黑色素瘤治疗。在本报告中，我们描述了一名71岁男性的病例，他在接受维莫非尼单药治疗非黑色素瘤癌症（具体为BRAF V600突变阳性的转移性肺腺癌）时出现了典型的GA皮损。
《皮肤药物学杂志》。2017年；16(10):1050 - 1052。
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