在病毒增殖周期中，爱泼斯坦-巴尔病毒核抗原-1的表达无变化。
Unchanged expression of Epstein-Barr virus-determined nuclear antigen-1 in productive virus cycle.
作者信息
Nováková Z, Krchnák V, Roubal J
机构信息
Department of Experimental Virology, Institute of Sera and Vaccines, Prague, Czechoslovakia.
出版信息
Acta Virol. 1988 Jul;32(4):349-52.
The level of the Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA-1) encoded by the Bam HI-K fragment of EBV DNA remained unchanged in P3HR-1 cells after induction of the productive cycle of virus replication by sodium-n-butyrate and 12-o-tetradecanoylphorbol-13-acetate (TPA). This was shown by the same capacity of cell-free extracts from untreated and treated P3HR-1 cells to absorb anti-EBNA-1 antibody from a known human serum.
用正丁酸钠和12 - O -十四烷酰佛波醇-13 -乙酸酯（TPA）诱导P3HR - 1细胞进入病毒复制的增殖周期后，EBV DNA的Bam HI - K片段编码的爱泼斯坦-巴尔病毒（EBV）核抗原（EBNA - 1）水平保持不变。这是通过未处理和处理后的P3HR - 1细胞的无细胞提取物从已知人血清中吸收抗EBNA - 1抗体的能力相同来证明的。
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