Moulin M, Hugues F C, Bigot M C, Mosquet B
Centre Régional de Pharmacovigilance, Caen.
Allerg Immunol (Paris). 1988 Oct;20(8):306, 309, 311.
It has been established that the use of beta-2 sympathomimetic aerosols is a safe and efficacious treatment of asthma. Unexpected cases of sudden death amongst insufficiently-treated patients or patients who stopped their treatment are not linked with the use of these drugs. To assess the risk of possible "receptor desensitization" it is necessary to notify these accidents to the Committee on Safety of Drugs and to take into consideration the opposite results of further administration and termination of treatment.
已经证实，使用β-2拟交感神经气雾剂是治疗哮喘的一种安全有效的方法。在治疗不充分的患者或停止治疗的患者中出现的意外猝死病例与使用这些药物无关。为了评估可能的“受体脱敏”风险，有必要将这些事故通报给药品安全委员会，并考虑进一步给药和终止治疗的相反结果。
