Department of Microbiology, School of Basic Medical Sciences, Anhui Provincial Laboratory of Microbiology and Parasitology; Anhui Key Laboratory of Zoonoses, Anhui Medical University, China.
Anhui Center for Disease Control and Prevention (Anhui CDC), China.
Infect Genet Evol. 2017 Dec;56:14-18. doi: 10.1016/j.meegid.2017.10.014. Epub 2017 Oct 14.
We conducted an investigation of Orientia tsutsugamushi infection among rodents in non-endemic areas in Anhui Province. Fifty-six (56) rodents including 44 Apodemus agrarius and 12 Niviventer niviventer were trapped and captured in autumn in the fields of three counties in Anhui Province. DNA samples were amplified and sequenced for the 56kDa protein gene of Orientia tsutsugamushi. The overall infection rate in the rodents was 23.2%(13/56). The rate of detection of O. tsutsugamushi in Apodemus agrarius and Niviventer niviventer were 27.3% and 8.3% respectively. Moreover, we identified two genotypes (Karp and Gilliam strains) of Orientia tsutsugamushi in rodents. Our study demonstrated that Apodemus agrarius is the main host for O. tsutsugamushi pathogen and this is the first report of Karp and Gilliam strains in these non-endemic areas in Anhui Province.
我们对安徽省非流行地区的恙虫病东方体感染进行了调查。在安徽省三个县的田间，于秋季捕获了 56 只（56 只）啮齿动物，包括 44 只东方田鼠和 12 只黑线姬鼠。扩增和测序了恙虫病东方体的 56kDa 蛋白基因的 DNA 样本。啮齿动物的总感染率为 23.2%（13/56）。在东方田鼠和黑线姬鼠中检测到恙虫病东方体的比例分别为 27.3%和 8.3%。此外，我们在啮齿动物中鉴定出两种基因型（Karp 和 Gilliam 株）的恙虫病东方体。我们的研究表明，东方田鼠是恙虫病东方体病原体的主要宿主，这是安徽省非流行地区首次报告 Karp 和 Gilliam 株。
