Suppr超能文献

[儿童及青少年多发性硬化症:复杂、慢性且具有差异性]

[Multiple sclerosis in childhood and adolescence : Complex, chronic and differentiated].

作者信息

Blaschek A, Huppke P, Kümpfel T, Müller-Felber W, Rostasy K

机构信息

Pädiatrische Neurologie, Zentrum für neuromuskuläre Erkrankungen und Neuroimmunologie im Kindesalter, LMU Zentrum - iSPZ Hauner, Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital, Universität München, München, Deutschland.

Abteilung Pädiatrische Neurologie, Entwicklungsneurologie und Sozialpädiatrie, Dr. von Haunersches Kinderspital, Ludwig-Maximilians-Universität München, Lindwurmstraße 4, 80337, München, Deutschland.

出版信息

Nervenarzt. 2017 Dec;88(12):1377-1384. doi: 10.1007/s00115-017-0422-z.

Abstract

Pediatric multiple sclerosis (MS) is one of the most important acquired neurological disorders in childhood and adolescence. A timely recognition, diagnosis and treatment are of utmost importance. This article highlights the current state of knowledge on the etiology, pathogenesis, diagnosis, clinical presentation and treatment in childhood. Although the rate of progression of disability in the early years is slower in younger patients compared to adults, a disease-modifying therapy should be started once MS is diagnosed.

摘要

小儿多发性硬化症(MS)是儿童和青少年时期最重要的后天性神经系统疾病之一。及时识别、诊断和治疗至关重要。本文重点介绍了儿童MS在病因、发病机制、诊断、临床表现和治疗方面的当前知识状况。尽管与成人相比,年轻患者在疾病早期的残疾进展速度较慢,但一旦确诊MS,就应开始使用疾病修正疗法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验