Martel Arnaud
a Department of Ophthalmology , University Hospital of Nice , Nice , France.
Orbit. 2018 Apr;37(2):94-96. doi: 10.1080/01676830.2017.1383458. Epub 2017 Oct 17.
An 86-year-old patient was hospitalized for fever and left acute orbital syndrome (red eye with moderate visual impairment, chemosis, ophthalmoplegia without proptosis, or any fundus involvement). CT scan showed superior ophthalmic vein and cavernous sinus enlargement complicating ipsilateral sphenoidal sinusitis. Magnetic resonance imaging (MRI) demonstrated the left cavernous sinus thrombosis extended to the ipsilateral jugular vein and transversal sinus (Lemierre syndrome). Intravenous broad-spectrum antibiotics and curative anticoagulation were prescribed. Blood cultures allowed the identification of Streptococcus intermedius and Staphylococcus warneri species. Evolution was favorable and the patient was discharged 3 weeks after. Antibiotics and anticoagulation were carried out for a total duration of 4 and 12 weeks, respectively. Lemierre syndrome is a potentially life-threatening emergency rarely encountered; thus, ophthalmologists should be cognizant of clinical and radiological features. Broad-spectrum antibiotics are the mainstay of treatment. Curative anticoagulation may be added if no blood coagulation disorder nor bleeding on neuroimaging has been identified.
一名86岁患者因发热和左侧急性眼眶综合征(眼红伴中度视力损害、球结膜水肿、无眼球突出的眼肌麻痹或任何眼底受累)入院。CT扫描显示眼上静脉和海绵窦扩大,并发同侧蝶窦炎。磁共振成像(MRI)显示左侧海绵窦血栓形成延伸至同侧颈静脉和横窦(勒米尔综合征)。给予静脉注射广谱抗生素和治疗性抗凝。血培养鉴定出中间型链球菌和沃纳葡萄球菌。病情好转,患者在3周后出院。抗生素和抗凝治疗的总疗程分别为4周和12周。勒米尔综合征是一种罕见的、可能危及生命的急症;因此,眼科医生应了解其临床和放射学特征。广谱抗生素是主要治疗方法。如果未发现凝血障碍或神经影像学上无出血,则可加用治疗性抗凝。