Ishikawa Toru, Imai Michitaka, Owaki Takashi, Sato Hiroki, Nozawa Yujiro, Sano Tomoe, Iwanaga Akito, Seki Keiichi, Honma Terasu, Yoshida Toshiaki, Kudo Masatoshi
Department of Gastroenterology and Hepatology, Saiseikai Niigata Daini Hospital, Niigata, Japan.
Dig Dis. 2017;35(6):598-601. doi: 10.1159/000480255. Epub 2017 Oct 17.
BACKGROUND/AIM: Balloon-occluded transcatheter arterial chemoembolization (B-TACE) using miriplatin (MPT) is anticipated as a new strategy for hepatocellular carcinoma (HCC). This study was aimed at evaluating the hemodynamic changes with/without balloon occlusion of the hepatic artery, correlation of cone-beam CT (CBCT) pixels, and CT value after B-TACE for HCC.
A total of 52 patients with HCC, who underwent B-TACE using MPT in addition to the balloon-occluded CBCT hepatic arteriography, were studied.
After balloon occlusion, CBCT pixel values increased in 37 lesions, whereas it decreased in 15 lesions. Intratumoral CT values after B-TACE were lower with decreased CBCT pixel values than with increased CBCT pixel values.
Hemodynamic changes on CBCT during balloon occlusion can be used to predict the efficacy of B-TACE using MPT.
背景/目的：使用米铂（MPT）的球囊闭塞经导管动脉化疗栓塞术（B-TACE）有望成为肝细胞癌（HCC）的一种新策略。本研究旨在评估肝动脉球囊闭塞与否时的血流动力学变化、锥形束CT（CBCT）像素的相关性以及HCC患者接受B-TACE后的CT值。
对52例接受了使用MPT的B-TACE以及球囊闭塞CBCT肝动脉造影的HCC患者进行了研究。
球囊闭塞后，37个病灶的CBCT像素值增加，而15个病灶的像素值降低。B-TACE后瘤内CT值在CBCT像素值降低时低于像素值增加时。
球囊闭塞期间CBCT上的血流动力学变化可用于预测使用MPT的B-TACE的疗效。
