Geroin C, Squintani G, Morini A, Donato F, Smania Nicola, Gandolfi Maria Giovanna, Tamburin S, Fasano Alfonso, Tinazzi Michele
Funct Neurol. 2017 Jul/Sep;32(3):143-151. doi: 10.11138/fneur/2017.32.3.143.
Patients with Parkinson's disease (PD) and Pisa syndrome (PS) may present tonic dystonic or compensatory (i.e. acting against gravity) hyperactivity in the paraspinal and non-paraspinal muscles. Electromyographic (EMG) activity was measured in nine patients with PD and PS, three with PD without PS, and five healthy controls. Fine-wire intramuscular electrodes were inserted bilaterally into the iliocostalis lumborum (ICL), iliocostalis thoracis (ICT), gluteus medius (GM), and external oblique (EO) muscles. The root mean square (RMS) of the EMG signal was calculated and normalized for each muscle. In stance condition, side-to-side muscle activity comparisons showed a higher RMS only for the contralateral ICL in PD patients with PS (p=0.028). Moreover, with increasing degrees of lateral flexion, the activity of the EO and the ICL muscles progressively increased and decreased, respectively. The present data suggest that contralateral paraspinal muscle activity plays a crucial compensatory role and can be dysfunctional in PD patients with PS.
帕金森病（PD）和 Pisa 综合征（PS）患者的椎旁肌和非椎旁肌可能会出现强直性肌张力障碍或代偿性（即对抗重力）活动亢进。对 9 例 PD 合并 PS 患者、3 例无 PS 的 PD 患者及 5 名健康对照者进行了肌电图（EMG）活动测量。将细针肌内电极双侧插入腰髂肋肌（ICL）、胸髂肋肌（ICT）、臀中肌（GM）和腹外斜肌（EO）。计算每块肌肉 EMG 信号的均方根（RMS）并进行标准化。在站立状态下，肌肉活动的左右对比显示，PS 的 PD 患者仅对侧 ICL 的 RMS 较高（p = 0.028）。此外，随着侧屈程度增加，EO 和 ICL 肌肉的活动分别逐渐增加和减少。目前的数据表明，对侧椎旁肌活动起关键的代偿作用，且在合并 PS 的 PD 患者中可能存在功能障碍。
