Engin-Ustun Yaprak, Yılmaz Nafiye, Akgun Nilufer, Aktulay Ayla, Tuzluoğlu Ahmet Deniz, Bakırarar Batuhan
Zekai Tahir Burak Education and Research Hospital, Reproductive Endocrinology Unit, Ankara, Turkey.
Zekai Tahir Burak Education and Research Hospital, Reproductive Endocrinology Unit, Ankara, Turkey.
Int J Fertil Steril. 2018 Jan;11(4):258-262. doi: 10.22074/ijfs.2018.4888. Epub 2017 Oct 12.
The aim of this study is to evaluate the relationship between sperm parameters and body mass index (BMI) in the male spouses with infertility complaints, who had reffered to our clinic.
The male spouses from 159 couples reffering to our clinic because of infertility, during a six-month period, were included in the study. In this prospective case control study, the included men were categorized as non-obese (BMIP<25 kg/m), overweight (BMI 25-29 kg/m) and obese (BMI ≥30 kg/m) according to their BMIs. The assessed sperm parameters consisted of; sperm concentration, Kruger morphology, progressive motility level, and volume pH levels. The statistical significant level was set as less than 0.05.
The assessed group consisted of 159 patients applying to our clinic with infertility symptoms. Fifty-three non-obese, 53 overweight and 53 obese men were eligible for the study. There was statistically significant differences in sperm volume (P<0.001), progressive motility (P<0.001), postwash sperm count (P<0.001) and Kruger (P<0.001) morphology among the patient groups grouping according to the BMI levels.
In this study, increased BMI was associated with decreased semen quality, affecting volume, concentration, and motility. further studies with a wider range of prospective cases need to be conducted in order to investigate the effects on male fertility in more detail.
本研究旨在评估前来我院就诊的有不孕问题的男性配偶的精子参数与体重指数(BMI)之间的关系。
本研究纳入了在六个月期间因不孕前来我院就诊的159对夫妇中的男性配偶。在这项前瞻性病例对照研究中,根据BMI将纳入的男性分为非肥胖(BMI<25kg/m²)、超重(BMI 25-29kg/m²)和肥胖(BMI≥30kg/m²)。评估的精子参数包括:精子浓度、克鲁格形态、前向运动水平和体积pH值。统计学显著性水平设定为小于0.05。
评估组由159例有不孕症状前来我院就诊的患者组成。53名非肥胖、53名超重和53名肥胖男性符合研究条件。根据BMI水平分组的患者组之间,精子体积(P<0.001)、前向运动(P<0.001)、洗涤后精子计数(P<0.001)和克鲁格形态(P<0.001)存在统计学显著差异。
在本研究中,BMI升高与精液质量下降有关,影响体积、浓度和活力。为了更详细地研究对男性生育能力的影响,需要进行更广泛的前瞻性病例的进一步研究。