犬尿喹啉酸和AP5可区分NMDA受体激动剂。
Kynurenic acid and AP5 distinguish between NMDA receptor agonists.
作者信息
Williams T L, Stone T W, Burton N R, Smith D A
机构信息
Department of Physiology, St. George's Hospital Medical School, London, United Kingdom.
出版信息
Exp Neurol. 1988 Dec;102(3):366-7. doi: 10.1016/0014-4886(88)90232-4.
PMID:2904376
Abstract
Quantitative analysis of responses to amino acids in mouse cortical slices has indicated that the antagonists kynurenate and 2-amino-5-phosphonopentanoic acid distinguish between ibotenate and both N-methyl-D-aspartate (NMDA) and quinolinate. This result is consistent with the existence of NMDA-receptor subtypes.
摘要
对小鼠皮质切片中氨基酸反应的定量分析表明，拮抗剂犬尿烯酸和2-氨基-5-磷酸戊酸可区分鹅膏蕈氨酸与N-甲基-D-天冬氨酸（NMDA）及喹啉酸。该结果与NMDA受体亚型的存在相一致。
Zotero 插件