Rondy Marc, Gherasim Alin, Casado Itziar, Launay Odile, Rizzo Caterina, Pitigoi Daniela, Mickiene Aukse, Marbus Sierk D, Machado Ausenda, Syrjänen Ritva K, Pem-Novose Iva, Horváth Judith Krisztina, Larrauri Amparo, Castilla Jesús, Vanhems Philippe, Alfonsi Valeria, Ivanciuc Alina E, Kuliese Monika, van Gageldonk-Lafeber Rianne, Gomez Veronica, Ikonen Niina, Lovric Zvjezdana, Ferenczi Annamária, Moren Alain
EpiConcept, Paris, France.
National Centre of Epidemiology, Institute of Health Carlos III, Madrid, Spain.
Euro Surveill. 2017 Oct;22(41). doi: 10.2807/1560-7917.ES.2017.22.41.17-00645.
In a multicentre European hospital study we measured influenza vaccine effectiveness (IVE) against A(H3N2) in 2016/17. Adjusted IVE was 17% (95% confidence interval (CI): 1 to 31) overall; 25% (95% CI: 2 to 43) among 65-79-year-olds and 13% (95% CI: -15 to 30) among those ≥ 80 years. As the A(H3N2) vaccine component has not changed for 2017/18, physicians and public health experts should be aware that IVE could be low where A(H3N2) viruses predominate.
在一项欧洲多中心医院研究中,我们测定了2016/17年度流感疫苗针对A(H3N2)的有效性(IVE)。总体调整后的IVE为17%(95%置信区间(CI):1%至31%);65至79岁人群中为25%(95%CI:2%至43%),80岁及以上人群中为13%(95%CI:-15%至30%)。由于2017/18年度A(H3N2)疫苗成分未变,医生和公共卫生专家应意识到,在A(H3N2)病毒占主导的地区,IVE可能较低。