Department of Chemistry, University of Swabi, Anbar-23561, Khyber Pakhtunkhwa, Pakistan.
Food Funct. 2017 Dec 13;8(12):4284-4305. doi: 10.1039/c7fo01300k.
Many natural products present in our diet, including flavonoids, can prevent the progression of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and vegetables, plays an important role as a therapeutic and chemopreventive agent used in the treatment of various illnesses. It exhibits effects against different types of cancer through different pathways. It additionally exerts antidiabetic, anti-inflammatory, and anti-oxidant effects in a variety of cell types. Furthermore, the cardiovascular protective capacities of resveratrol are associated with multiple molecular targets and may lead to the development of novel therapeutic strategies for atherosclerosis, ischemia/reperfusion, metabolic syndrome, and heart failure. Accordingly, this article presents an overview of recent developments in the use of resveratrol for the prevention and treatment of different diseases along with various mechanisms. In addition, the present review summarizes the most recent literature pertaining to resveratrol as a chemotherapeutic agent against multiple diseases and provides an assessment of the potential of this natural compound as a complementary or alternative medicine.
许多存在于我们饮食中的天然产物，包括类黄酮，可以预防癌症和其他疾病的进展。白藜芦醇是一种存在于各种水果和蔬菜中的天然多酚，作为一种治疗和化学预防剂，在治疗各种疾病方面发挥着重要作用。它通过不同途径对不同类型的癌症表现出作用。此外，它在多种细胞类型中具有抗糖尿病、抗炎和抗氧化作用。此外，白藜芦醇的心血管保护能力与多个分子靶点相关，可能导致动脉粥样硬化、缺血/再灌注、代谢综合征和心力衰竭等疾病的新型治疗策略的发展。因此，本文综述了白藜芦醇在预防和治疗不同疾病中的最新研究进展及其相关机制。此外，本综述总结了有关白藜芦醇作为多种疾病化学治疗剂的最新文献，并评估了这种天然化合物作为补充或替代医学的潜力。
