Guérin P, Berriche S, Intrator S, Rouger P, Salmon D, Salmon C, Lucotte G
Laboratoire de Génétique Moléculaire, Institut National de Transfusion Sanguine, Paris.
Rev Fr Transfus Immunohematol. 1988 Oct;31(3):513-20. doi: 10.1016/s0338-4535(88)80052-7.
The Y specific probe (two 49f and 49a sub-clones) is a polymorphic one for the A (5 alleles), C (2 alleles), D (3 alleles), F (2 alleles) and I (2 alleles). We show that the corresponding allelic combinations, or haplotypes, are transmitted father-to-son in eleven random chosen families. Utilisation of these polymorphisms in other eleven father-son paternitity cases, studied for a panel of erythrocytic and seric markers, shows a good correlation between the two approaches, most of the paternies excluded by the Y probes being also excluded with other allotypic markers. Utilisation of this sort of polymorphism does not necessitate the knowledge of maternal genotype in families studied.
Y特异性探针（两个49f和49a亚克隆）对于A（5个等位基因）、C（2个等位基因）、D（3个等位基因）、F（2个等位基因）和I（2个等位基因）是多态性的。我们表明，在随机选择的11个家庭中，相应的等位基因组合或单倍型是从父亲传给儿子的。在另外11个父子亲子鉴定案例中使用这些多态性，这些案例针对一组红细胞和血清标记物进行了研究，结果表明两种方法之间具有良好的相关性，大多数被Y探针排除的父子关系也被其他同种异型标记物排除。在研究的家庭中使用这种多态性不需要了解母亲的基因型。
