Mekki Q A, Turner P
Department of Clinical Pharmacology, St Bartholomew's Hospital Medical College, London.
Br J Clin Pharmacol. 1988 Jul;26(1):89-91. doi: 10.1111/j.1365-2125.1988.tb03368.x.
Two oral doses of cicloprolol (50 mg and 100 mg), a beta 1-adrenoceptor partial agonist, were administered to nine healthy volunteers in a double-blind placebo-controlled study. Intraocular pressure (IOP) and exercise heart rate were reduced while the resting heart rate and blood pressure remained unchanged. The responses to the two different doses of cicloprolol were similar.
在一项双盲安慰剂对照研究中，对9名健康志愿者口服给予两剂环丙洛尔（50毫克和100毫克），其为β1肾上腺素能受体部分激动剂。眼压（IOP）和运动心率降低，而静息心率和血压保持不变。对两种不同剂量环丙洛尔的反应相似。
