环丙洛尔对健康志愿者眼压的影响。
Effect of cicloprolol in intraocular pressure in healthy volunteers.
作者信息
Mekki Q A, Turner P
机构信息
Department of Clinical Pharmacology, St Bartholomew's Hospital Medical College, London.
出版信息
Br J Clin Pharmacol. 1988 Jul;26(1):89-91. doi: 10.1111/j.1365-2125.1988.tb03368.x.
Abstract
Two oral doses of cicloprolol (50 mg and 100 mg), a beta 1-adrenoceptor partial agonist, were administered to nine healthy volunteers in a double-blind placebo-controlled study. Intraocular pressure (IOP) and exercise heart rate were reduced while the resting heart rate and blood pressure remained unchanged. The responses to the two different doses of cicloprolol were similar.
摘要
在一项双盲安慰剂对照研究中，对9名健康志愿者口服给予两剂环丙洛尔（50毫克和100毫克），其为β1肾上腺素能受体部分激动剂。眼压（IOP）和运动心率降低，而静息心率和血压保持不变。对两种不同剂量环丙洛尔的反应相似。
相似文献
1
Effect of cicloprolol in intraocular pressure in healthy volunteers.环丙洛尔对健康志愿者眼压的影响。
Br J Clin Pharmacol. 1988 Jul;26(1):89-91. doi: 10.1111/j.1365-2125.1988.tb03368.x.
2
Studies of the agonist and antagonist activity of cicloprolol in man.环丙洛尔在人体中的激动剂和拮抗剂活性研究。
Eur J Clin Pharmacol. 1988;34(6):569-75. doi: 10.1007/BF00615219.
3
Comparative analysis of beta-1 adrenoceptor agonist and antagonist potency and selectivity of cicloprolol, xamoterol and pindolol.环丙洛尔、扎莫特罗和吲哚洛尔对β-1肾上腺素能受体激动剂及拮抗剂效能和选择性的比较分析
J Pharmacol Exp Ther. 1987 Sep;242(3):1025-34.
4
An evaluation of the safety of the beta-modulator cicloprolol in chronic heart failure.β-调节剂环丙洛尔在慢性心力衰竭中的安全性评估。
Clin Cardiol. 1992 Jan;15(1):38-42. doi: 10.1002/clc.4960150109.
5
Combined invasive and noninvasive study of left ventricular systolic and diastolic function following acute administration of cicloprolol to subjects with normal cardiac function.对心功能正常的受试者急性给予环丙洛尔后左心室收缩和舒张功能的侵入性与非侵入性联合研究。
Cardiovasc Drugs Ther. 1992 Oct;6(5):513-7. doi: 10.1007/BF00055610.
6
An assessment of the partial agonist activity of Ro 31-1118, flusoxolol and pindolol in man.罗 31-1118、氟索洛尔和吲哚洛尔在人体中的部分激动剂活性评估。
Br J Clin Pharmacol. 1987 Nov;24(5):571-80. doi: 10.1111/j.1365-2125.1987.tb03215.x.
7
A comparison of esmolol and dexmedetomidine for attenuation of intraocular pressure and haemodynamic responses to laryngoscopy and tracheal intubation.艾司洛尔与右美托咪定对喉镜检查和气管插管引起的眼压及血流动力学反应的抑制作用比较。
Eur J Anaesthesiol. 2008 Jun;25(6):517-9. doi: 10.1017/S0265021508003529. Epub 2008 Feb 1.
8
Effect of CGP 17/582, a selective beta-adrenoceptor antagonist, on the haemodynamic and hypokalaemic response to adrenaline.选择性β-肾上腺素能受体拮抗剂CGP 17/582对肾上腺素引起的血流动力学和低钾血症反应的影响。
Br J Clin Pharmacol. 1989 May;27(5):553-61. doi: 10.1111/j.1365-2125.1989.tb03417.x.
9
Pharmacodynamic without pharmacokinetic interaction between cicloprolol, a partial beta 1-adrenoceptor agonist, and digoxin in healthy subjects.在健康受试者中，部分β1肾上腺素能受体激动剂环丙洛尔与地高辛之间不存在药代动力学相互作用的药效学。
Br J Clin Pharmacol. 1990 Sep;30(3):411-6. doi: 10.1111/j.1365-2125.1990.tb03792.x.
10
Effect of orally administered nadolol on the intraocular pressure in normal volunteers.口服纳多洛尔对正常志愿者眼压的影响。
Br J Ophthalmol. 1985 Jan;69(1):38-40. doi: 10.1136/bjo.69.1.38.
本文引用的文献
1
Effects of topical betaxolol in ocular hypertensive patients.局部用倍他洛尔对高眼压症患者的影响。
Arch Ophthalmol. 1984 Apr;102(4):539-40. doi: 10.1001/archopht.1984.01040030417014.
2
Respiratory effects of timolol.
N Engl J Med. 1984 Nov 29;311(22):1441. doi: 10.1056/nejm198411293112213.
3
Carteolol: preliminary study on ocular pressure-reducing action.卡替洛尔：眼压降低作用的初步研究。
Ophthalmologica. 1983;187(3):171-3. doi: 10.1159/000309320.
4
A new tonometer system.
Am J Optom Arch Am Acad Optom. 1972 Aug;49(8):646-60. doi: 10.1097/00006324-197208000-00005.
5
Ocular hypotensive effect of atenolol (Tenormin, I.C.I.). A new beta-adrenergic blocker.阿替洛尔（氨酰心安，帝国化学工业公司产品）的降眼压作用。一种新型β-肾上腺素能阻滞剂。
Br J Ophthalmol. 1975 Jun;59(6):296-300. doi: 10.1136/bjo.59.6.296.
Zotero 插件