Children's Health Children's Medical Center Dallas.
University of Texas Southwestern Medical Center.
J Pediatr Psychol. 2018 Mar 1;43(2):152-161. doi: 10.1093/jpepsy/jsx097.
To examine hope and its components of agency and pathways as predictors of anxiety and depressive symptoms in children receiving cancer treatment.
Sixty patients (mean standard deviation age = 13.3 (2.7); 57% male) completed Snyder's Hope Scales, the Children's Depression Inventory, and the State-Trait Anxiety Inventory at diagnosis and 3 month intervals for 1 year following pediatric cancer diagnosis. Parents also completed Snyder's Hope Scales. Linear mixed-effect regression was used to assess hope's role in longitudinal models of symptoms of depression and anxiety.
Agency was a significant predictor of between-patient differences and within-patient changes in symptoms of depression and anxiety. Neither patient pathways nor either component of parent hope was predictive of symptoms of depression or anxiety. Patients who were more likely to have depressive symptoms at baseline were older, diagnosed with leukemia, and non-Hispanic White as opposed to Hispanic. Patient demographics were not predictive of anxiety.
Patient agency is a potential target for intervention to prevent or reduce anxiety and depressive symptoms following pediatric cancer diagnosis.
探讨希望及其效能感和路径两个成分对接受癌症治疗的儿童焦虑和抑郁症状的预测作用。
60 名患者（平均标准差年龄=13.3（2.7）；57%为男性）在诊断时以及在儿科癌症诊断后 1 年内每 3 个月接受一次斯奈德希望量表、儿童抑郁量表和状态-特质焦虑量表评估。家长还完成了斯奈德希望量表。线性混合效应回归用于评估希望在抑郁和焦虑症状的纵向模型中的作用。
效能感是预测抑郁和焦虑症状的个体间差异和个体内变化的重要指标。父母希望的两个组成部分和患者的路径都不能预测抑郁或焦虑症状。基线时更有可能出现抑郁症状的患者年龄较大，被诊断为白血病，且为非西班牙裔白人，而非西班牙裔。患者人口统计学特征不能预测焦虑。
患者效能感是预防或减少儿科癌症诊断后焦虑和抑郁症状的潜在干预靶点。
