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[后腹腔镜输尿管切开取石术与输尿管软镜钬激光碎石术治疗复杂性上段输尿管结石的疗效]

[Effects of retroperitoneal laparoscopic ureterolithotomy and flexible-ureteroscopic holmium laser lithotripsy for complex upper ureteral calculi].

作者信息

Zhang L J, Wu B, Zha Z L, Zhao H, Yang W, Chen X H, Jiang B, Huang Q, Li W J, Yuan J

机构信息

Department of Urology, Affiliated Jiangyin Hospital of Southeast University Medical College, Jiangyin 214400, Jiangsu Province, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2017 Oct 1;55(10):751-754. doi: 10.3760/cma.j.issn.0529-5815.2017.10.007.

Abstract

To explore the clinical effects of retroperitoneal laparoscopic ureterolithotomy (RPLU) and flexible-ureteroscopic holmium laser lithotripsy (f-UHLL) for complicated upper ureteral calculi. A total of 45 cases of complicated upper ureteral calculi between March 2014 and January 2016 in Department of Urology, Affiliated Jiangyin Hospital of Southeast University Medical College were retrospectively analyzed, there were 32 males and 13 females, ranging from 27 to 45 years with an average age of (34.1±9.5) years. Of the 45 patients, 28 had ureteral distortion and 17 had concurrent ureteral stones in the lower or middle ipsilateral ureter. In those patients, 20 cases underwent f-UHLL, and 25 cases received RPLU. The stone size, operation time, hospital stay, stone clearance rates and postoperative fever rates between the two groups were compared with test and χ(2)test. The operation was successfully performed in all patients, no complications with leakage of urine or ureteral perforation occurred, and no significant difference in renal function between the two methods were founded in postoperative period. There was no significant difference in operation time((78.4±8.5) minuetes .(73.3±11.3) minuetes, =0.61, =0.67), time of double J tube removed ((33.8±3.4)days . (37.6±8.9) d, =2.37, =0.08) and ipsilateral renal glomerular filtration rates ((41.3±7.6)ml/minuetes .(40.5±7.1) ml/min, =0.78, =1.27) between the two groups. However, the hospitalization time ((5.9±1.7)days . (4.2±1.6) days, =1.92, =0.04), postoperative fever rates (4% .30%, χ(2)=5.72, =0.03) and calculus clearance rates (100% . 75%, χ(2)=7.03, =0.01) in RPLU were significantly higher than f-UHLL. Besides, 5 patients in the f-UHLL group had postoperative stone residue and were treated with extracorpore shock wave lithotripsy. Both RPLU and f-UHLL are safety and validity for complex upper ureteral calculi. RPLU can improve the rate of calculus removal and reduce the rate of postoperative fever.

摘要

探讨后腹腔镜输尿管切开取石术(RPLU)与输尿管软镜钬激光碎石术(f-UHLL)治疗复杂性上尿路结石的临床效果。回顾性分析2014年3月至2016年1月东南大学医学院附属江阴医院泌尿外科收治的45例复杂性上尿路结石患者,其中男32例,女13例,年龄27~45岁,平均(34.1±9.5)岁。45例患者中,输尿管扭曲28例,同侧输尿管中下段合并结石17例。将20例行f-UHLL治疗,25例行RPLU治疗。采用t检验和χ²检验比较两组患者结石大小、手术时间、住院时间、结石清除率及术后发热率。所有患者手术均成功,无尿漏、输尿管穿孔等并发症发生,术后两组肾功能差异无统计学意义。两组手术时间[(78.4±8.5)分钟 (73.3±11.3)分钟,t=0.61,P=0.67]、双J管拔除时间[(33.8±3.4)天 (37.6±8.9)天,t=2.37,P=0.08]及同侧肾肾小球滤过率[(41.3±7.6)ml/分钟 (40.5±7.1)ml/分钟,t=0.78,P=1.27]差异无统计学意义。但RPLU组住院时间[(5.9±1.7)天 (4.2±1.6)天,t=1.92,P=0.04]、术后发热率(4% 30%,χ²=5.72,P=0.03)及结石清除率(100% 75%,χ²=7.03,P=0.01)均显著高于f-UHLL组。此外,f-UHLL组有5例患者术后结石残留,行体外冲击波碎石治疗。RPLU和f-UHLL治疗复杂性上尿路结石均安全有效。RPLU可提高结石清除率,降低术后发热率。

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