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猫爪草

Uncaria tomentosa.

作者信息

Della Valle Valentina

机构信息

Unit of Dermatology, Department of Medical-Surgical Physiopathology and Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy -

出版信息

G Ital Dermatol Venereol. 2017 Dec;152(6):651-657. doi: 10.23736/S0392-0488.17.05712-1.

DOI:10.23736/S0392-0488.17.05712-1
PMID:29050447
Abstract

Uncaria tomentosa (U. tomentosa) or uña de gato, a species of vine of Rubiaceae family, was used from centuries in various medical conditions. Although there are no randomized controlled trials or published human outcome studies, some conditions reportedly improved by U. tomentosa include osteoarthritis, rheumatoid arthritis, prostatitis, viral illnesses and cancer (acting as a non-specific immunomodulantign agent) and it may also have potential as an immunomodulating adaptogen in cellular aging. The understanding of some specific mechanisms of molecular action leads to the demonstration of various anti-inflammatory, immunostimulating and protective effects. These results bring the strong hypothesis that U. tomentosa could be effective in the topical treatment of dermatological manifestation, namely rosacea.

摘要

猫爪草,即茜草科的一种藤本植物,数世纪以来一直被用于治疗各种疾病。虽然没有随机对照试验或已发表的人体疗效研究,但据报道,猫爪草改善的一些病症包括骨关节炎、类风湿性关节炎、前列腺炎、病毒性疾病和癌症(作为一种非特异性免疫调节因子),并且它在细胞衰老方面作为免疫调节适应原可能也有潜力。对一些特定分子作用机制的了解导致了各种抗炎、免疫刺激和保护作用的证明。这些结果有力地支持了一个假设,即猫爪草可能对酒渣鼻等皮肤病表现的局部治疗有效。

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Uncaria tomentosa.猫爪草
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Uncaria tomentosa Leaves Decoction Modulates Differently ROS Production in Cancer and Normal Cells, and Effects Cisplatin Cytotoxicity.猫爪草叶煎剂对癌细胞和正常细胞中活性氧生成的调节作用不同,并影响顺铂的细胞毒性。
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Two new nor-triterpene glycosides from peruvian "Uña de Gato" (Uncaria tomentosa).从秘鲁“猫爪藤”(钩藤)中分离出的两种新的去甲三萜糖苷。
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Uncaria tomentosa acts as a potent TNF-alpha inhibitor through NF-kappaB.钩藤通过 NF-κB 发挥强效 TNF-α 抑制剂的作用。
J Ethnopharmacol. 2010 Feb 17;127(3):685-93. doi: 10.1016/j.jep.2009.12.004. Epub 2009 Dec 6.

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