Population genetics of the globin genes in Polynesians.
作者信息
Trent R J, Mickleson K N, Yakas J, Hertzberg M
机构信息
Molecular Biology Laboratory, University of Sydney, NSW, Australia.
出版信息
Hemoglobin. 1988;12(5-6):533-7. doi: 10.3109/03630268808991642.
PMID:2905345
Abstract
Globin gene mapping data enable Polynesians to be divided into three distinct groups: (i) Maoris, Cook Islanders, (ii) Tongans, Samoans, (iii) Niue Islanders. Unusual RFLPs detected by the restriction enzymes Apa I and Bgl II are found in Polynesians. A high frequency of alpha-thalassemia in this population is explained by genetic drift and a founder effect.
摘要
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