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伊伐布雷定用于先天性心脏病术后交界性异位性心动过速

Ivabradine for junctional ectopic tachycardia in post congenital heart surgery.

作者信息

Kumar Vivek, Kumar Gaurav, Joshi Sajan, Sharma Vipul

机构信息

Army hospital R&R, India.

Army hospital R&R, India.

出版信息

Indian Heart J. 2017 Sep-Oct;69(5):666-667. doi: 10.1016/j.ihj.2017.09.007. Epub 2017 Sep 14.

DOI:10.1016/j.ihj.2017.09.007
PMID:29054199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5650559/
Abstract

We report two cases of malignant junctional ectopic tachycardia (JET), in infants following congenital heart surgery. After the failure of conventional therapy the arrhythmia was controlled by oral Ivabradine, a drug which is routinely used to lower heart rate in angina and heart failure in adult practice.

摘要

我们报告了两例先天性心脏手术后婴儿发生恶性交界性异位性心动过速（JET）的病例。在传统治疗失败后，心律失常通过口服伊伐布雷定得到控制，伊伐布雷定是一种在成人实践中常用于降低心绞痛和心力衰竭患者心率的药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac3e/5650559/701f42008821/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac3e/5650559/701f42008821/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac3e/5650559/701f42008821/gr1.jpg

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本文引用的文献

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Adjunctive ivabradine in combination with amiodarone: A novel therapy for pediatric congenital junctional ectopic tachycardia.伊伐布雷定联合胺碘酮：小儿先天性交界性异位性心动过速的一种新疗法。
Heart Rhythm. 2016 Jun;13(6):1297-302. doi: 10.1016/j.hrthm.2016.03.015.
2
Post cardiac surgery junctional ectopic tachycardia: A 'Hit and Run' tachyarrhythmia as yet unchecked.心脏手术后交界性异位性心动过速：一种尚未得到控制的“来去匆匆”的快速性心律失常。
Ann Pediatr Cardiol. 2014 Jan;7(1):25-8. doi: 10.4103/0974-2069.126545.
3
Potential new indication for ivabradine: treatment of a patient with congenital junctional ectopic tachycardia.
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HeartRhythm Case Rep. 2022 Mar 18;8(6):415-419. doi: 10.1016/j.hrcr.2022.03.011. eCollection 2022 Jun.
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The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium Channels.心动过缓药物伊伐布雷定作为电压门控钠通道的非典型抑制剂。
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