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一项关于早产儿腹股沟疝修补时机预测因素的多机构分析。

A multi-institution analysis of predictors of timing of inguinal hernia repair among premature infants.

作者信息

Gulack Brian C, Greenberg Rachel, Clark Reese H, Miranda Marie Lynn, Blakely Martin L, Rice Henry E, Adibe Obinna O, Tracy Elisabeth T, Smith P Brian

机构信息

Department of Surgery, Duke University Medical Center, Durham, NC; Duke Clinical Research Institute, Durham, NC.

Department of Pediatrics, Duke University Medical Center, Durham, NC; Duke Clinical Research Institute, Durham, NC.

出版信息

J Pediatr Surg. 2018 Apr;53(4):784-788. doi: 10.1016/j.jpedsurg.2017.09.009. Epub 2017 Sep 23.

Abstract

PURPOSE

Inguinal hernias are common in premature infants, but there is substantial variation with regards to timing of repair. We sought to quantify and explain this variation.

METHODS

Cohort study of infants <34weeks gestation diagnosed with an inguinal hernia and discharged from one of 329 neonatal intensive units between 1998 and 2012. Multivariable logistic regression clustered by site was used to evaluate demographic, clinical, maternal, and socioeconomic variables associated with pre-discharge repair.

RESULTS

A total of 8037 infants met study criteria, and 3230 (40%) received a pre-discharge repair. The frequency of pre-discharge repair varied by site from 9% to 84%, and increased over the study period from 20% in 1998 to 45% in 2012. Concurrent gastrostomy or fundoplication and lower socioeconomic status were associated with an increased odds of receiving a pre-discharge repair.

CONCLUSION

There is substantial variation with regards to the timing of repair of inguinal hernias in premature infants, with an increasing number of infants receiving repair prior to hospital discharge over time. Concurrent gastrostomy or fundoplication and socioeconomic status are associated with timing of repair.

LEVEL OF EVIDENCE

IV.

摘要

目的

腹股沟疝在早产儿中很常见,但修补时机存在很大差异。我们试图对这种差异进行量化并加以解释。

方法

对1998年至2012年间在329个新生儿重症监护病房之一诊断为腹股沟疝并出院的孕周<34周的婴儿进行队列研究。采用按部位聚类的多变量逻辑回归来评估与出院前修补相关的人口统计学、临床、母亲和社会经济变量。

结果

共有8037名婴儿符合研究标准,其中3230名(40%)在出院前接受了修补。出院前修补的频率因部位而异,从9%到84%不等,且在研究期间从1998年的20%增加到2012年的45%。同时进行胃造口术或胃底折叠术以及社会经济地位较低与出院前接受修补的几率增加有关。

结论

早产儿腹股沟疝修补时机存在很大差异,随着时间的推移,越来越多的婴儿在出院前接受修补。同时进行胃造口术或胃底折叠术以及社会经济地位与修补时机有关。

证据级别

IV级。

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本文引用的文献

3
Inguinal hernia repair in premature infants: more questions than answers.早产儿腹股沟疝修补术:问题多于答案。
Arch Dis Child Fetal Neonatal Ed. 2015 Jul;100(4):F286-8. doi: 10.1136/archdischild-2012-302964. Epub 2015 Feb 20.
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Does timing of neonatal inguinal hernia repair affect outcomes?新生儿腹股沟疝修补术的时机是否会影响手术结果?
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