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[散发性和家族性嗜铬细胞瘤的外科治疗]

[Surgical therapy of sporadic and familial pheochromocytoma].

作者信息

Dralle H, Ipta M, Henschel E, Schürmeyer T, Grosse H, Gratz K F, Kemnitz J, von zur Mühlen A

机构信息

Klinik für Abdominal- und Transplantationschirurgie, Medizinischen Hochschule Hannover, BRD.

出版信息

Acta Med Austriaca. 1988;15(4):108-10.

PMID:2905563
Abstract

From 1975 through 1987, 54 patients underwent operations for pheochromocytoma (PCC): 37 patients for sporadic unilateral adrenal PCC, 9 for bilateral and familial PCC, and 4 patients for paraganglioma. In 4 additional patients, laparotomy failed to discover the reason for hypercatecholaminemia. There were no operative mortality and a low morbidity for unilateral (n = 43) as well as for bilateral adrenalectomy (n = 6). To avoid hormone replacement therapy after bilateral total adrenalectomy at least for some years, unilateral instead of bilateral adrenalectomy was preferred to be the initial surgical procedure of choice for familial and MEN-IIA-associated unilateral adrenal PCC. Autologous transplantation of the adrenal cortex were performed in 2 patients after bilateral adrenalectomy. 6 months postoperatively, the transplants were vital as proved by light-microscopy, but sufficiently functioning only in 1 patient.

摘要

1975年至1987年期间,54例患者接受了嗜铬细胞瘤(PCC)手术:37例为散发性单侧肾上腺PCC,9例为双侧和家族性PCC,4例为副神经节瘤。另有4例患者,剖腹手术未能发现高儿茶酚胺血症的原因。单侧肾上腺切除术(n = 43)和双侧肾上腺切除术(n = 6)均无手术死亡且发病率低。为了至少在几年内避免双侧全肾上腺切除术后的激素替代治疗,对于家族性和MEN-IIA相关的单侧肾上腺PCC,首选单侧而非双侧肾上腺切除术作为初始手术方式。2例患者在双侧肾上腺切除术后进行了肾上腺皮质自体移植。术后6个月,光镜检查证明移植组织存活,但仅1例患者移植组织功能足够。

相似文献

1
[Surgical therapy of sporadic and familial pheochromocytoma].[散发性和家族性嗜铬细胞瘤的外科治疗]
Acta Med Austriaca. 1988;15(4):108-10.
2
Surgical aspects of familial pheochromocytoma.
Horm Metab Res Suppl. 1989;21:34-8.
3
Surgical management of hereditary pheochromocytoma.遗传性嗜铬细胞瘤的外科治疗
J Am Coll Surg. 2004 Apr;198(4):525-34; discussion 534-5. doi: 10.1016/j.jamcollsurg.2003.12.001.
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Estimated risk of pheochromocytoma recurrence after adrenal-sparing surgery in patients with multiple endocrine neoplasia type 2A.2A 型多发性内分泌腺瘤病患者行肾上腺保留手术后嗜铬细胞瘤复发的估计风险。
Arch Surg. 2006 Dec;141(12):1199-205; discussion 1205. doi: 10.1001/archsurg.141.12.1199.
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[Subtotal adrenalectomy versus autotransplantation of the adrenal cortex--an alternative procedure in bilateral adrenalectomy in MEN II?].
Chirurg. 1989 Apr;60(4):266-71; discussion 271-2.
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[Subtotal bilateral adrenalectomy preserving adrenocortical function].保留肾上腺皮质功能的双侧肾上腺次全切除术
Chirurg. 2003 Jul;74(7):646-51. doi: 10.1007/s00104-002-0608-0.
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Management of hereditary pheochromocytoma in von Hippel-Lindau kindreds with partial adrenalectomy.对患有冯·希佩尔-林道综合征家族性遗传性嗜铬细胞瘤患者进行肾上腺部分切除术的治疗
J Urol. 1999 Feb;161(2):395-8.
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Subtotal adrenalectomy for phaeochromocytoma in multiple endocrine neoplasia type 2A.2A型多发性内分泌腺瘤病中嗜铬细胞瘤的肾上腺次全切除术
Eur J Surg. 1999 Jun;165(6):535-8. doi: 10.1080/110241599750006415.
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Pheochromocytoma: inherited associations, bilaterality, and cortex preservation.嗜铬细胞瘤:遗传关联、双侧性及皮质保留
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引用本文的文献

1
"The" pheochromocytoma: a benign, intra-adrenal, hypertensive, sporadic unilateral tumor. Does it exist?“典型的”嗜铬细胞瘤:一种良性、肾上腺内、高血压性、散发性单侧肿瘤。它存在吗?
World J Surg. 1994 Jul-Aug;18(4):467-72. doi: 10.1007/BF00353738.