Bourgeois M
Centre Carreire, Bordeaux.
Encephale. 1988 Sep;14 Spec No:195-201.
In France chlorpromazine was used as soon as 1952, and TD were described very early (Ey et al., 1956; Sigwald et al., 1959). Nevertheless there is very little interest in this complication of neuroleptic treatment. The mild oral syndrome is neglected and severe TD considered as very rare, due to lower dosage of neuroleptics in France. We summarize several inquiries: Maurel et al. (1966; prevalence = 49%), Bourgeois (1976-1977; 8.1%), Bourgeois et al. in a sample of 270 elderly (prevalence = 42.4% with neuroleptics; 18% in patients who never received neuroleptics), Delance (1985 = 16%), Fanget et al. (1986; 3.8%).
在法国,氯丙嗪早在1952年就已被使用,迟发性运动障碍也很早就有描述(艾伊等人,1956年;西格瓦尔德等人,1959年)。然而,人们对这种抗精神病药物治疗的并发症兴趣寥寥。由于法国抗精神病药物的剂量较低,轻度口腔综合征被忽视,严重的迟发性运动障碍被认为非常罕见。我们总结了几项调查:莫雷尔等人(1966年;患病率=49%)、布尔乔亚(1976 - 1977年;8.1%)、布尔乔亚等人在270名老年人的样本中(使用抗精神病药物的患病率=42.4%;从未接受过抗精神病药物治疗的患者中为18%)、德兰斯(1985年=16%)、方热等人(1986年;3.8%)。