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犬黏液瘤性二尖瓣疾病的诊断与治疗方法综述

Review of Diagnostic and Therapeutic Approach to Canine Myxomatous Mitral Valve Disease.

作者信息

Menciotti Giulio, Borgarelli Michele

机构信息

Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, 205 Duck Pond Dr., Blacksburg, VA 24061, USA.

出版信息

Vet Sci. 2017 Sep 26;4(4):47. doi: 10.3390/vetsci4040047.

DOI:10.3390/vetsci4040047
PMID:29056705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5753627/
Abstract

The most common heart disease that affects dogs is myxomatous mitral valve disease. In this article, we review the current diagnostic and therapeutic approaches to this disease, and we also present some of the latest technological advancements in this field.

摘要

影响犬类的最常见心脏病是黏液瘤性二尖瓣疾病。在本文中,我们回顾了针对该疾病的当前诊断和治疗方法,并且还介绍了该领域的一些最新技术进展。

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Review of Diagnostic and Therapeutic Approach to Canine Myxomatous Mitral Valve Disease.犬黏液瘤性二尖瓣疾病的诊断与治疗方法综述
Vet Sci. 2017 Sep 26;4(4):47. doi: 10.3390/vetsci4040047.
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Interstitial cells from dogs with naturally occurring myxomatous mitral valve disease undergo phenotype transformation.患有自然发生的黏液瘤样二尖瓣疾病的犬的间质细胞会发生表型转化。
J Heart Valve Dis. 2008 Jul;17(4):402-11; discussion 412.
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Vet J. 2018 Feb;232:16-19. doi: 10.1016/j.tvjl.2017.12.002. Epub 2017 Dec 5.
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Structural and cellular changes in canine myxomatous mitral valve disease: an image analysis study.犬黏液瘤样二尖瓣疾病的结构和细胞变化:一项图像分析研究。
J Heart Valve Dis. 2010 Jan;19(1):60-70.
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Tryptophan hydroxylase 1 expression is increased in phenotype-altered canine and human degenerative myxomatous mitral valves.色氨酸羟化酶1在表型改变的犬类和人类退行性黏液瘤样二尖瓣中表达增加。
J Heart Valve Dis. 2010 Jan;19(1):71-8.
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Apoptosis and abundance of Bcl-2 family and transforming growth factor β1 signaling proteins in canine myxomatous mitral valves.犬黏液瘤样二尖瓣中细胞凋亡以及Bcl-2家族和转化生长因子β1信号蛋白的丰度
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Murmur intensity in small-breed dogs with myxomatous mitral valve disease reflects disease severity.患有黏液瘤性二尖瓣疾病的小型犬的杂音强度反映了疾病的严重程度。
J Small Anim Pract. 2014 Nov;55(11):545-50. doi: 10.1111/jsap.12265. Epub 2014 Sep 12.

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Vet Sci. 2025 Mar 2;12(3):223. doi: 10.3390/vetsci12030223.
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Self-Reported Utilization of International Guidelines for Staging Dogs with Myxomatous Mitral Valve Degeneration: A Survey among Veterinary Practitioners.自我报告的犬黏液瘤性二尖瓣退化分期国际指南应用情况:兽医从业者调查
Vet Sci. 2023 Dec 2;10(12):687. doi: 10.3390/vetsci10120687.
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Evaluation of antioxidant status and lipid peroxidation in dogs with myxomatous mitral valve degeneration stage B1.

本文引用的文献

1
Mitral valve repair in dogs using an ePTFE chordal implantation device: a pilot study.使用ePTFE腱索植入装置对犬进行二尖瓣修复:一项初步研究。
J Vet Cardiol. 2017 Jun;19(3):256-267. doi: 10.1016/j.jvc.2017.03.002. Epub 2017 May 31.
2
Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels.二尖瓣反流严重程度和左心室收缩维度可预测年轻查理士王小猎犬的生存率。
J Vet Intern Med. 2017 Jul;31(4):1008-1016. doi: 10.1111/jvim.14759. Epub 2017 Jun 1.
3
Transcatheter Mitral Valve Interventions: Current Therapies and Future Directions.
B1期黏液瘤样二尖瓣退化犬抗氧化状态和脂质过氧化的评估。
Front Vet Sci. 2023 Sep 6;10:1203480. doi: 10.3389/fvets.2023.1203480. eCollection 2023.
4
Correlation between the Leaflet-Annulus Index and Echocardiographic Indices in Maltese Dogs with Myxomatous Mitral Valve Disease.患有黏液瘤样二尖瓣疾病的马尔济斯犬瓣环指数与超声心动图指数之间的相关性
Vet Sci. 2023 Aug 1;10(8):493. doi: 10.3390/vetsci10080493.
5
Sacubitril/valsartan mitigates cardiac remodeling, systolic dysfunction, and preserves mitochondrial quality in a rat model of mitral regurgitation.沙库巴曲缬沙坦减轻二尖瓣反流大鼠模型的心脏重构、收缩功能障碍和维持线粒体质量。
Sci Rep. 2023 Jul 16;13(1):11472. doi: 10.1038/s41598-023-38694-6.
6
Morphogeometric Evaluation of the Left Ventricle and Left Atrioventricular Ring in Dogs: A Computerized Anatomical Study.犬左心室和左房室环的形态几何学评估:一项计算机化解剖学研究
Animals (Basel). 2023 Jun 15;13(12):1996. doi: 10.3390/ani13121996.
7
Use of proposed systolic and myocardial performance indices derived from simultaneous ECG and PCG recordings to assess cardiac function in healthy Beagles.利用从同步心电图和心音图记录中得出的拟议收缩期和心肌性能指标评估健康比格犬的心脏功能。
Vet World. 2022 Jul;15(7):1785-1797. doi: 10.14202/vetworld.2022.1785-1797. Epub 2022 Jul 25.
8
Pro-Inflammatory and Immunological Profile of Dogs with Myxomatous Mitral Valve Disease.患有黏液瘤样二尖瓣疾病犬的促炎和免疫特征
Vet Sci. 2022 Jun 28;9(7):326. doi: 10.3390/vetsci9070326.
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Vet Sci. 2021 Sep 4;8(9):183. doi: 10.3390/vetsci8090183.
经导管二尖瓣介入治疗:当前疗法与未来方向
Curr Treat Options Cardiovasc Med. 2017 May;19(5):32. doi: 10.1007/s11936-017-0538-2.
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Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation: A Report from the American Society of Echocardiography Developed in Collaboration with the Society for Cardiovascular Magnetic Resonance.原发性瓣膜反流的非侵入性评估建议:美国超声心动图学会与心血管磁共振学会合作制定的报告
J Am Soc Echocardiogr. 2017 Apr;30(4):303-371. doi: 10.1016/j.echo.2017.01.007. Epub 2017 Mar 14.
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J Vet Cardiol. 2017 Apr;19(2):113-123. doi: 10.1016/j.jvc.2017.01.002. Epub 2017 Mar 7.
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Advanced imaging in valvular heart disease.瓣膜性心脏病的高级影像学检查。
Nat Rev Cardiol. 2017 Apr;14(4):209-223. doi: 10.1038/nrcardio.2017.1. Epub 2017 Jan 27.
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Left atrial volume and function in dogs with naturally occurring myxomatous mitral valve disease.自然发生黏液瘤样二尖瓣疾病犬的左心房容积与功能
J Vet Cardiol. 2017 Feb;19(1):24-34. doi: 10.1016/j.jvc.2016.08.006. Epub 2016 Nov 5.
8
Effect of Pimobendan in Dogs with Preclinical Myxomatous Mitral Valve Disease and Cardiomegaly: The EPIC Study-A Randomized Clinical Trial.匹莫苯丹对患有临床前期黏液瘤性二尖瓣疾病和心脏肥大犬的影响:EPIC研究——一项随机临床试验。
J Vet Intern Med. 2016 Nov;30(6):1765-1779. doi: 10.1111/jvim.14586. Epub 2016 Sep 28.
9
Transapical Beating-Heart Mitral Valve Repair With an Expanded Polytetrafluoroethylene Cordal Implantation Device: Initial Clinical Experience.经心尖跳动心脏二尖瓣修复术联合膨体聚四氟乙烯腱索植入装置:初步临床经验
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J Vet Intern Med. 2016 May;30(3):697-705. doi: 10.1111/jvim.13940.