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两例不同分级少突胶质细胞瘤的脊柱转移:病例报告及文献复习

Spinal metastases of two different grade oligodendrogliomas: a case report and review of literature.

作者信息

Maiguel Carrizosa Carlos Enrique, Sanchez Paez Maria Gabriela, Martinez Amado Andreina, Gonzalez Gutierrez Andrea, Garcia Ardila Maria Emma

机构信息

Neurological Surgery Department Foscal Clinic, Floridablanca, Colombia.

Nueva Granada Military University, Bogotá, Colombia.

出版信息

J Spine Surg. 2017 Sep;3(3):468-474. doi: 10.21037/jss.2017.06.14.

DOI:10.21037/jss.2017.06.14
PMID:29057359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5637209/
Abstract

Oligodendrogliomas (OGD) are glial tumors, together with mixed oligoastrocytoma constituting 5-20% of all gliomas, which occur predominantly in younger populations and are managed with surgery and chemotherapy with good long-term prognosis after treatment and additionally present with low rates of metastases. We present the case of a 46-year-old patient with intracranial right frontal subcortical OGD [World Health Organisation (WHO) grade II] managed at the Neurosurgery Department in Foscal Clinic, Floridablanca, Colombia. Two years after brain surgery the patient presents with neurological symptomatology suggestive of spinal cord compression and is found to have a neoplastic lesion with extra medullary compressive strength on the conus medullary and wrapping all of the roots with the final report of pathology and immunohistochemistry indicating: OGD (WHO grade III), this lesion was the only one found, the brain studies shows any residual tumor or recurrence in the primary tumor site.

摘要

少突胶质细胞瘤(OGD)是一种胶质瘤,与混合性少突星形细胞瘤一起占所有胶质瘤的5%-20%,主要发生在较年轻人群中,通过手术和化疗进行治疗,治疗后长期预后良好,且转移率较低。我们报告一例46岁患有颅内右额叶皮质下少突胶质细胞瘤(世界卫生组织(WHO)二级)的患者,该患者在哥伦比亚弗洛里达布兰卡市福斯卡尔诊所神经外科接受治疗。脑手术后两年,患者出现提示脊髓受压的神经症状,经检查发现有一个髓外压迫性肿瘤病变,位于圆锥髓质并包裹所有神经根,病理和免疫组化最终报告显示:少突胶质细胞瘤(WHO三级),此病变是唯一发现的病变,脑部检查未显示原发肿瘤部位有任何残留肿瘤或复发。

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