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Assessment of rehabilitation potential in patients with vascular dysfunction caused by undifferentiated connective tissue dysplasia.

作者信息

Solyeykо Olena V, Osypenko Iryna P, Galych Tetyana V, Chernykh Mariya O

机构信息

Vinnytsia National M.I.Pirogov Memorial Medical University, Vinnytsia, Ukraine.

Public Higher Educational Establishment "The Academy Of Continuing Education", Vinnytsia, Ukraine.

出版信息

Wiad Lek. 2017;70(2 pt 2):282-285.

PMID:29059643
Abstract

INTRODUCTION

Degradation of collagen, inherent to undifferentiated connective tissue dysplasia (UCTD) syndrome, also influences the changes in the structure of vascular walls. This contributes to the development of configured vascular anomalies, which are an independent predictor of vascular accident risk. Such diversity of UCTD manifestations requires development of prognostic criteria for rehabilitation potential, correction of which may contribute to recovery process in case of development of vascular catastrophe. Study aim is to evaluate the rehabilitation potential in patients with vascular dysfunction and underlying UCTD.

MATERIALS AND METHODS

The study involved 150 male patients with confirmed diagnosis of UCTD (average age - 26.4 ± 0.6 years). All patients had a complex clinical and instrumental examination. Phenotypic and UCTD visceral stigmas, UCTD biochemical markers were analyzed, followed by statistical processing of the results by method of variotional statistics.

RESULTS

We revealed the high degree of direct correlation between the presence of vascular dysfunction and myxomatous degeneration of the mitral valve (r = + 0.76, p.

摘要

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