Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul;2017:1376-1379. doi: 10.1109/EMBC.2017.8037089.
The aim of this study was to investigate the time difference (TD) between the onset of uterine contraction (UC) determined from tocodynamometry (TOCO) and identified by maternal perception. The online available Icelandic database was used to calculate TD, which was defined as the difference between when it was felt by a pregnant woman and the starting point on the UC signal recorded by a TOCO. A total of 295 TDs from 78 recordings (from a total of 33 participants; among them, 13 participants included at least 3 recordings from different gestational weeks) were analyzed with the overall mean±SD of TD calculated. For each individual participant with at least 3 recordings, regression analysis was then performed to investigate the relationship between the mean TD from each recording with gestational week, with their overall slope calculated. The results showed that 85.4% of TDs was within [-40, 40] s, with an overall mean TD of 3.04 s (p>0.05), indicating that there was no significant difference between the UC onset determined from TOCO and maternal perception. It was also noticed that 61.5% recordings (48 out of 78 recordings) had all positive or negative TD for all the UCs analyzed within a recording. Furthermore, the regression analysis showed that the regression line slope was negative for 10 out of the 13 participants with at least 3 recordings from different gestational weeks, resulting in that the overall slope (-2.85±5.58) was significantly negative (p<;0.05), and indicating that UC onset TD decreased with gestational weeks. In summary, this study quantitatively investigated the TD between the onset of UCs determined from TOCO and maternal perception, providing scientific evidence for future studies to understand the underlying mechanism of the time sequence of UC activity determined from different techniques.
本研究的目的是调查通过宫缩图（TOCO）确定的子宫收缩（UC）开始时间与孕妇感知到的子宫收缩开始时间之间的时间差（TD）。利用在线可用的冰岛数据库计算TD，TD定义为孕妇感觉到子宫收缩的时间与TOCO记录的UC信号起始点之间的差值。对来自78次记录（共33名参与者；其中，13名参与者包括来自不同孕周的至少3次记录）的总共295个TD进行了分析，并计算了TD的总体均值±标准差。然后，对每个至少有3次记录的个体参与者进行回归分析，以研究每次记录的平均TD与孕周之间的关系，并计算其总体斜率。结果显示，85.4%的TD在[-40,40]秒内，总体平均TD为3.04秒（p>0.05），表明通过TOCO确定的UC开始时间与孕妇感知之间没有显著差异。还注意到，在78次记录中有61.5%（48次记录）的所有分析的UC的TD均为正值或负值。此外，回归分析显示，在13名来自不同孕周且至少有3次记录的参与者中，有10名参与者的回归线斜率为负，导致总体斜率（-2.85±5.58）显著为负（p<0.05），表明UC开始TD随孕周增加而减小。总之，本研究定量调查了通过TOCO确定的UC开始时间与孕妇感知之间的TD，为未来研究了解通过不同技术确定的UC活动时间序列的潜在机制提供了科学依据。
