Volek Eva, Toth Jeannette, Nagy Zoltan Zsolt, Schneider Miklos
St. Lazarus Hospital, Salgotarjan, Hungary.
2nd Department of Pathology, Semmelweis University, Budapest, Hungary.
BMC Ophthalmol. 2017 Oct 23;17(1):194. doi: 10.1186/s12886-017-0588-y.
Conjunctival lymphangiectasia is a rare condition presumably caused by the obstruction of lymphatic channels or by an abnormal connection between conjunctival lymphatic and blood vessels. Diagnosis is based on clinical appearance and histology. We report a case of conjunctival lymphangiectasia in which anterior segment optical coherence tomography (OCT) was used to assist the diagnosis and the planning of the biopsy location.
A 31-year-old woman was referred with repeated episodes of conjunctival "hemorrhages" and chemosis with extended recovery periods over the last months. Other symptoms were dryness, redness, burning sensation and itching. Photo documentation, anterior segment OCT, ultrasound, computer tomography (CT) and magnetic resonance imaging (MRI) of the brain were performed. MRI revealed dilated atypical Virchow-Robin space (VRS). Conjunctival biopsy was taken and the location of the biopsy was selected based on OCT findings. Based on the clinical appearance we suspected the case to be conjunctival lymphangiectasia or lymphangioma. Histology and immunhistochemistry confirmed the diagnosis of conjunctival lymphangiectasia.
Anterior segment OCT is a non-invasive tool, useful in the evaluation of conjunctival lesions and planning surgery.
结膜淋巴管扩张是一种罕见病症,可能由淋巴管阻塞或结膜淋巴管与血管之间的异常连接所致。诊断基于临床表现和组织学检查。我们报告一例结膜淋巴管扩张病例,其中使用前段光学相干断层扫描(OCT)辅助诊断并规划活检部位。
一名31岁女性因在过去几个月中反复出现结膜“出血”和结膜水肿且恢复时间延长而前来就诊。其他症状包括眼干、眼红、烧灼感和瘙痒。进行了眼部照相记录、前段OCT、超声、脑部计算机断层扫描(CT)和磁共振成像(MRI)检查。MRI显示非典型的扩张的Virchow-Robin间隙(VRS)。根据OCT检查结果选择部位进行结膜活检。基于临床表现,我们怀疑该病例为结膜淋巴管扩张或淋巴管瘤。组织学和免疫组织化学检查确诊为结膜淋巴管扩张。
前段OCT是一种无创工具,有助于评估结膜病变并规划手术。