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眼前节光学相干断层扫描在结膜眼表疾病中的应用——综述

Anterior segment optical coherence tomography in conjunctival ocular surface disorders - A review.

作者信息

Rajagopal Rama, Vijayaraghavan Mridula, Jothi Balaji Janarthanam, Jayavel Karthick

机构信息

Department of Cornea and Refractive Surgery, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

Department of Optometry, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

出版信息

Indian J Ophthalmol. 2025 Apr 1;73(4):543-552. doi: 10.4103/IJO.IJO_68_25. Epub 2025 Mar 27.

DOI:10.4103/IJO.IJO_68_25
PMID:40146141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12097423/
Abstract

Ocular surface disorders involving the conjunctiva have a myriad of clinical presentations requiring considerable clinical acumen for an accurate diagnosis. There can also be an overlap in clinical features, resulting in a diagnostic dilemma. Over the last few years, anterior segment optical coherence tomography (AS-OCT), by its ability to provide an optical biopsy of the tissue of interest, has evolved as an important diagnostic device. Besides complimenting clinical diagnosis, it also helps in quantifying the response to topical chemotherapy and aids as a follow-up tool. In this review, we highlight the role of AS-OCT in various ocular surface disorders with relevant literature review.

摘要

涉及结膜的眼表疾病有众多临床表现，需要相当的临床敏锐度才能准确诊断。临床特征也可能存在重叠，从而导致诊断困境。在过去几年中，眼前节光学相干断层扫描（AS-OCT）凭借其对感兴趣组织进行光学活检的能力，已发展成为一种重要的诊断设备。除了辅助临床诊断外，它还有助于量化局部化疗的反应，并作为一种随访工具。在本综述中，我们通过相关文献回顾强调AS-OCT在各种眼表疾病中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/c2dbfb7182c3/IJO-73-543-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/9219e8aa48cd/IJO-73-543-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/8d5037db7f72/IJO-73-543-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/c26b78479780/IJO-73-543-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/d83310af349d/IJO-73-543-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/a511659b728e/IJO-73-543-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/fac80e858e4f/IJO-73-543-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/c2dbfb7182c3/IJO-73-543-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/9219e8aa48cd/IJO-73-543-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/8d5037db7f72/IJO-73-543-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/c26b78479780/IJO-73-543-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/d83310af349d/IJO-73-543-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/a511659b728e/IJO-73-543-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/fac80e858e4f/IJO-73-543-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/584c/12097423/c2dbfb7182c3/IJO-73-543-g007.jpg

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本文引用的文献

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Association between Tomographic Characteristics of Pterygium and Preoperative Anterior and Posterior Topography Measured by Anterior Segment Optical Coherence Tomography.翼状胬肉的断层扫描特征与术前眼前节光学相干断层扫描测量的前后表面地形图之间的关联
Life (Basel). 2024 Sep 29;14(10):1245. doi: 10.3390/life14101245.
2
Prospective Study: Utility of Anterior Segment Optical Coherence Tomography to Identify Predictive Factors of Recurrence in Pterygium Surgery.前瞻性研究：眼前节光学相干断层扫描在识别翼状胬肉手术复发预测因素中的应用
J Clin Med. 2024 Aug 14;13(16):4769. doi: 10.3390/jcm13164769.
3
Characteristics of conjunctival myxomas on anterior segment optical coherence tomography.
眼前节光学相干断层扫描下结膜黏液瘤的特征
Can J Ophthalmol. 2024 Dec;59(6):e865-e871. doi: 10.1016/j.jcjo.2024.06.008. Epub 2024 Jul 31.
4
Conjunctival Nevus.结膜痣
Curr Ophthalmol Rep. 2023 Dec;11(4):104-112. doi: 10.1007/s40135-023-00315-w. Epub 2023 Jul 19.
5
Correction: Anterior segment optical coherence tomography in ocular surface tumours and simulating lesions.更正：眼前节光学相干断层扫描在眼表肿瘤及模拟病变中的应用
Eye (Lond). 2023 Nov;37(16):3517-3518. doi: 10.1038/s41433-023-02541-9.
6
Anterior segment optical coherence tomography in ocular surface tumours and simulating lesions.眼前节光学相干断层扫描在眼表肿瘤和模拟病变中的应用。
Eye (Lond). 2023 Apr;37(5):925-937. doi: 10.1038/s41433-022-02339-1. Epub 2022 Dec 13.
7
Anterior segment optical coherence tomography characteristics of conjunctival papilloma as compared to papilliform ocular surface squamous neoplasia.眼前节光学相干断层扫描特征比较结膜乳头瘤与乳头瘤样眼表鳞状上皮瘤。
Eye (Lond). 2023 Apr;37(5):995-1001. doi: 10.1038/s41433-022-02309-7. Epub 2022 Nov 19.
8
High resolution anterior segment optical coherence tomography of ocular surface lesions: A review and handbook.眼表病变的高分辨率眼前节光学相干断层扫描：综述与手册
Expert Rev Ophthalmol. 2021;16(2):81-95. doi: 10.1080/17469899.2021.1851598. Epub 2020 Dec 28.
9
Role of AS-OCT in Managing Corneal Disorders.眼前节光学相干断层扫描在角膜疾病管理中的作用。
Diagnostics (Basel). 2022 Apr 7;12(4):918. doi: 10.3390/diagnostics12040918.
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The use of high resolution optical coherence tomography (HR-OCT) in the diagnosis of ocular surface masqueraders.高分辨率光学相干断层扫描（HR-OCT）在眼表伪装者诊断中的应用。
Ocul Surf. 2022 Apr;24:74-82. doi: 10.1016/j.jtos.2022.02.003. Epub 2022 Feb 26.