Murray D P, Tan L B, Salih M, Weissberg P, Murray R G, Littler W A
Department of Cardiovascular Medicine, University of Birmingham, East Birmingham Hospital.
Br Heart J. 1988 Dec;60(6):474-9. doi: 10.1136/hrt.60.6.474.
The influence of beta blockade on the ability of ST depression, during pre-discharge exercise testing, to predict coronary anatomy and subsequent complications was studied in 300 consecutive post-infarct patients, 125 of whom underwent cardiac catheterisation. At the time of exercise 62 patients were taking a beta blocker. The exercise test had a higher sensitivity in predicting multivessel disease in patients who were not taking beta blockers than in patients who were (95% v 76%). beta Blockade did not, however, influence the ability of the test to identify patients at risk of subsequent cardiac events (sensitivity 84% and 85% respectively). These results suggest that it is not necessary to stop treatment with beta blockers before predischarge exercise testing of patients who have had an acute myocardial infarction.
在300例连续的心肌梗死后患者中研究了β受体阻滞剂对出院前运动试验期间ST段压低预测冠状动脉解剖结构及随后并发症能力的影响，其中125例患者接受了心导管检查。运动时，62例患者正在服用β受体阻滞剂。运动试验在预测未服用β受体阻滞剂的患者多支血管病变方面比服用β受体阻滞剂的患者具有更高的敏感性（95%对76%）。然而，β受体阻滞剂并不影响该试验识别有随后心脏事件风险患者的能力（敏感性分别为84%和85%）。这些结果表明，在对急性心肌梗死患者进行出院前运动试验之前，没有必要停用β受体阻滞剂治疗。
