Department of Health Policy, The London School of Economics and Political Science, London, UK.
Mult Scler. 2018 Aug;24(9):1251-1255. doi: 10.1177/1352458517737388. Epub 2017 Oct 24.
The International MultiPlE Sclerosis Study (IMPrESS) studied the significant impact of multiple sclerosis (MS) on the health and well-being of both people with the disease and their caregivers, along with its broader socioeconomic impact. Results confirmed that there is an urgent need to achieve better outcomes for people with MS. This paper uses results from the IMPrESS to present new international evidence on the socioeconomic burden of MS and discuss the merits of a likely paradigm shift in the management of MS towards the use of better (and more accurate) diagnostic follow-up to monitor disease progression and the earlier use of disease-modifying treatments (DMTs) to achieve better clinical, quality-of-life and socioeconomic results for individuals.
国际多发性硬化症研究 (IMPrESS) 研究了多发性硬化症 (MS) 对患者及其护理人员的健康和福祉以及更广泛的社会经济影响的重大影响。结果证实，迫切需要为多发性硬化症患者实现更好的结果。本文利用 IMPrESS 的研究结果，提供了关于多发性硬化症社会经济负担的新国际证据，并讨论了在多发性硬化症管理方面可能出现的范式转变的优点，即转向使用更好（更准确）的诊断随访来监测疾病进展，以及更早使用疾病修正治疗 (DMT)，以实现个人更好的临床、生活质量和社会经济效益。
