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[从牙科角度看克罗恩病:文献综述]

[Dental perspective on Crohn's disease: literature review].

作者信息

Głowacka Beata, Radwan-Oczko Małgorzata

机构信息

Zakład Patologii Jamy Ustnej Przy Katedrze Periodontologii, Uniwersytet Medyczny, Wrocław, Polska.

出版信息

Wiad Lek. 2017;70(4):860-864.

Abstract

Crohn's disease (CD) is a chronic, idiophatic inflammatory process of the gastrointestinal tract and its cause remains unknown. It can affect any part of the digestive system, but preferentially involves the terminal part of the small intestine and the beginning of the large intestine. The disease course is usually long-term with episodes of remission and relapses. The clinical presentation of the disease varies and depends on the site of inflammation. Oral lesions can occur in 80% of pediatric and 90% of adult patients with CD. The most frequent are swelling of the oral mucosa with surface cobblestoning, ulcerations, candidiasis, angular cheilitis. The difficulty in diagnosis, resulting from the non-specific clinical manifestation, hamper proper diagnosis and delay the start of treatment. This paper presents etiology, epidemiology, clinical features and basic therapeutic capabilities for CD in the light of the literature. Oral manifestation of this disease was particularly emphasized.

摘要

克罗恩病(CD)是一种胃肠道的慢性特发性炎症性疾病,其病因尚不清楚。它可累及消化系统的任何部位,但优先累及小肠末端和大肠起始部。病程通常较长,有缓解期和复发期。该病的临床表现各异,取决于炎症部位。80%的儿童克罗恩病患者和90%的成年患者会出现口腔病变。最常见的是口腔黏膜肿胀伴表面鹅卵石样改变、溃疡、念珠菌病、口角炎。由于临床表现不具特异性,诊断困难,这妨碍了正确诊断并延误了治疗的开始。本文根据文献介绍了克罗恩病的病因、流行病学、临床特征及基本治疗方法。特别强调了该病的口腔表现。

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