Schubert M C, Stitz J, Cohen H S, Sangi-Haghpeykar H, Mulavara A P, Peters B T, Bloomberg J J
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
University of Applied Sciences/Upper Austria, Linz, Austria.
J Vestib Res. 2017;27(2-3):173-176. doi: 10.3233/VES-170618.
We have developed a non-invasive, behavioral measure of ocular alignment using a computer tablet, colored lenses, and touch screen software.
The goal of this study was to determine if these tests differentiate healthy controls from patients with vestibular disorders.
In the vertical alignment nulling test (VAN), subjects were asked to adjust a horizontal line that was offset vertically from a fixed horizontal line. In the torsional alignment nulling test (TAN) subjects were asked to adjust a line that was rotationally offset (i.e. clockwise) from a fixed horizontal line. We measured VAN and TAN in 14 healthy controls and 8 patients with known vestibular disorders.
Patients had significantly worse scores than controls on TAN, (mean 2.2 vs 0.75, p = 0.01), and no differences for scores compared to controls on VAN, (mean 0.4 vs 0.8, p = 0.07).
These results suggest that TAN, and possibly VAN, have potential for identifying misalignments in ocular position. After further technical development these tests might be useful in the future for screening patients in facilities that are not equipped to perform cervical and ocular vestibular evoked myogenic potentials.
我们利用电脑平板电脑、彩色镜片和触摸屏软件开发了一种用于测量眼位对准的非侵入性行为测量方法。
本研究的目的是确定这些测试能否区分健康对照者和前庭疾病患者。
在垂直对准归零测试（VAN）中，要求受试者调整一条与固定水平线垂直偏移的水平线。在扭转对准归零测试（TAN）中，要求受试者调整一条与固定水平线呈旋转偏移（即顺时针）的线。我们对14名健康对照者和8名已知前庭疾病患者进行了VAN和TAN测量。
患者在TAN上的得分显著低于对照者（平均2.2对0.75，p = 0.01），而在VAN上与对照者相比得分无差异（平均0.4对0.8，p = 0.07）。
这些结果表明，TAN以及可能的VAN在识别眼位失调方面具有潜力。经过进一步的技术开发，这些测试未来可能有助于在没有设备进行颈部和眼前庭诱发肌源性电位检测的机构中对患者进行筛查。
