Isaradisaikul S, Navacharoen N, Hanprasertpong C, Kangsanarak J
Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Thailand.
J Laryngol Otol. 2013 Sep;127(9):848-53. doi: 10.1017/S0022215113001655. Epub 2013 Aug 8.
To analyse cervical vestibular evoked myogenic potential response parameters in normal volunteers and vertiginous patients.
A prospective study of 50 normal subjects and 50 patients with vertigo was conducted at Chiang Mai University Hospital, Thailand. Cervical vestibular evoked myogenic potential responses were measured using air-conducted, 500-Hz, tone-burst stimuli with subjects in a sitting position with their head turned toward the contralateral shoulder.
The mean ± standard deviation age and male:female ratio in the normal (44.0 ± 9.3 years; 12:38) and vertigo groups (44.7 ± 9.8 years; 17:33) were not significantly different. The prevalence of absent responses in the normal (14 per cent) and vertigo ears (46 per cent) differed significantly (p < 0.0001). Other cervical vestibular evoked myogenic potential parameters (i.e. response threshold, P1 and N1 latency, P1–N1 interlatency and interamplitude, inter-ear difference in P1 threshold, and asymmetry ratio) showed no inter-group differences.
The absence of a cervical vestibular evoked myogenic potential response is useful in the identification of vestibular dysfunction. However, patients should undergo a comprehensive battery of other vestibular tests to supplement their cervical vestibular evoked myogenic potential response findings.
分析正常志愿者和眩晕患者的颈前庭诱发肌源性电位反应参数。
在泰国清迈大学医院对50名正常受试者和50名眩晕患者进行了一项前瞻性研究。使用气导、500赫兹、短纯音刺激,在受试者头部转向对侧肩部的坐姿下测量颈前庭诱发肌源性电位反应。
正常组(44.0±9.3岁;男12例,女38例)和眩晕组(44.7±9.8岁;男17例,女33例)的平均年龄±标准差及男女比例无显著差异。正常耳(14%)和眩晕耳(46%)无反应的发生率差异显著(p<0.0001)。其他颈前庭诱发肌源性电位参数(即反应阈值、P1和N1潜伏期、P1-N1峰间期和峰间幅值、P1阈值的双耳差异以及不对称率)在组间无差异。
颈前庭诱发肌源性电位反应缺失有助于识别前庭功能障碍。然而,患者应接受一系列其他前庭测试,以补充其颈前庭诱发肌源性电位反应的检查结果。