Girault J P, Lafont R, Kerb U
Université René Descartes, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS U.A. 400, Paris, France.
Drug Metab Dispos. 1988 Sep-Oct;16(5):716-20.
Ecdysone metabolism was investigated in the white mouse Mus musculus. It was shown to involve dehydroxylation at C-14, followed by reduction of ring B into a 6 alpha-hydroxy derivative and epimerization at C-3.
在小家鼠中对蜕皮激素代谢进行了研究。结果表明,其代谢过程包括在C-14位进行脱羟基化,随后将B环还原为6α-羟基衍生物,并在C-3位发生差向异构化。