Department of Bioscience and Biotechnology, Banasthali University, Banasthali, RAJ-304022, India.
Pace Junior College, Mumbai, Maharashtra 400028, India.
Crit Rev Oncol Hematol. 2017 Nov;119:13-22. doi: 10.1016/j.critrevonc.2017.09.004. Epub 2017 Sep 12.
Genistein is an isoflavone present in soy and is known to have multiple molecular effects, such as the inhibition of inflammation, promotion of apoptosis, and modulation of steroidal hormone receptors and metabolic pathways. Since these molecular effects impact carcinogenesis, cancer propagation, obesity, osteoporosis, and metabolic syndromes, genistein plays an important role in preventing and treating common disorders. The role of genistein has not been adequately evaluated in all these clinical settings. This review summarizes some of the known molecular effects of genistein and its potential role in health maintenance and treatment.
染料木黄酮是大豆中的一种异黄酮，具有多种分子作用，如抑制炎症、促进细胞凋亡、调节甾体激素受体和代谢途径。由于这些分子作用会影响癌症的发生、癌症的扩散、肥胖、骨质疏松和代谢综合征，染料木黄酮在预防和治疗常见疾病方面发挥着重要作用。在所有这些临床环境中，染料木黄酮的作用尚未得到充分评估。本文综述了染料木黄酮的一些已知分子作用及其在维持健康和治疗中的潜在作用。
