急性乙型肝炎病毒感染与严重非免疫性溶血性贫血：一种罕见的关联。
Acute hepatitis B virus infection and severe non-immune haemolytic anaemia: a rare relationship.
作者信息
Furtado Inês, Valadares Diana, Nery Filipe Gaio
机构信息
Internal Medicine Department, Centro Hospitalar do Porto, Porto, Portugal.
Department of Intensive Care, Centro Hospitalar do Porto, Porto, Portugal.
出版信息
BMJ Case Rep. 2017 Oct 24;2017:bcr-2017-221763. doi: 10.1136/bcr-2017-221763.
The clinical presentation of acute hepatitis B virus (HBV) infection is usually related to the onset of liver failure and damage. Anaemia may occur, but it is only rarely attributed to haemolysis. The authors report about the case of a 41-year-old woman with the diagnosis of acute HBV infection and coagulopathy (without encephalopathy) who developed non-immune haemolytic anaemia. Total recovery of the analytical liver profile, coagulopathy and anaemia was achieved through treatment targeting HBV.This case shows that, although rare, non-immune haemolytic anaemia may occur in association with acute HBV infection and that HBV suppression seems to lead to progressive anaemia resolution.
急性乙型肝炎病毒（HBV）感染的临床表现通常与肝衰竭和肝损伤的发作有关。可能会出现贫血，但很少归因于溶血。作者报告了一例41岁女性病例，该患者被诊断为急性HBV感染和凝血病（无肝性脑病），并发生了非免疫性溶血性贫血。通过针对HBV的治疗，肝脏分析指标、凝血病和贫血均完全恢复。该病例表明，虽然罕见，但非免疫性溶血性贫血可能与急性HBV感染相关，且抑制HBV似乎会导致贫血逐渐缓解。
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