Sagawa Masano, Yokomizo Hajime, Yoshimatsu Kazuhiko, Yano Yuki, Okayama Sachiyo, Sakuma Akiko, Satake Masaya, Yamada Yasufumi, Usui Takebumi, Yamaguchi Kentaro, Shiozawa Shunichi, Shimakawa Takeshi, Katsube Takao, Kato Hiroyuki, Naritaka Yoshihiko
Dept. of Surgery, Tokyo Women's Medical University Medical Center East.
Gan To Kagaku Ryoho. 2017 Oct;44(10):921-923.
We examined the relationship between risk factors for surgical site infections(SSIs)and prognosis in 440 patients who underwent colon cancer surgery. We evaluated factors related to SSIs(GradeB II)and compared survival rates by stage. SSIs were observed in 36 patients. An increased SSI incidence was associated with pulmonary dysfunction, mGPS=2, CONUT≥2, PNI≤40, NLR>4.3, location(rectum), depth of tumor invasion(Bsubserosa, SS), lymph node metastasis, laparotomy, resection of other organs, colostomy, blood loss(large), and operative time(long). Survival rates were lower in Stage II/III patients with SSIs. Preoperative risk judgment is important in colorectal cancer surgery.
我们研究了440例行结肠癌手术患者手术部位感染（SSIs）的危险因素与预后之间的关系。我们评估了与SSIs（B级II类）相关的因素，并按分期比较了生存率。36例患者发生了SSIs。SSIs发生率增加与肺功能障碍、改良格拉斯哥预后评分（mGPS）=2、控制营养状况的预后营养指数（CONUT）≥2、预后营养指数（PNI）≤40、中性粒细胞与淋巴细胞比值（NLR）>4.3、肿瘤位置（直肠）、肿瘤浸润深度（B浆膜下、浆膜层）、淋巴结转移、剖腹手术、其他器官切除、结肠造口术、失血量（大）和手术时间（长）有关。发生SSIs的II/III期患者生存率较低。术前风险判断在结直肠癌手术中很重要。
