Department of Reproductive Medicine, University of California-San Diego, La Jolla.
Department of Urology, University of California-San Diego, La Jolla.
JAMA. 2017 Oct 24;318(16):1592-1604. doi: 10.1001/jama.2017.12137.
Urinary incontinence, the involuntary loss of urine, is a common health condition that may decrease quality of life. Ten to twenty percent of women and up to 77% of women residing in nursing homes have urinary incontinence, yet only 25% seek or receive treatment.
This review summarizes the evaluation and therapeutic options for women affected by urinary incontinence. The initial assessment should focus on understanding the effect of incontinence on quality of life, the patient's goals and preferences for treatment, the results of previous treatments, and the presence of concomitant conditions, such as advanced pelvic organ prolapse, that may require referral. Infection and hematuria need to be ruled out. In the absence of urinary infection or serious underlying pathology (such as cancer or serious neurologic disease) associated with urinary incontinence, the clinician should initiate unsupervised pelvic muscle exercises and lifestyle modifications appropriate to the patient to reduce her symptoms. These recommendations can include weight loss, adequate hydration, avoidance of excessive fluids, and regular voiding intervals that reduce urgency incontinence episodes. Urgency incontinence medications, with timely reassessment of symptoms, can be started without extensive evaluation. Specialist treatments for urgency incontinence include onabotulinumtoxinA and percutaneous or implanted neuromodulators. Stress incontinence surgery, the midurethral sling, is associated with symptom improvement in 48% to 90% of women and has low rates of mesh complications (<5%).
Urinary incontinence is common in women, although few seek care despite many effective treatment options. Clinicians should prioritize urinary incontinence detection, identify and treat modifiable factors, incorporate patient preference into evaluation and treatment, initiate conservative and medical therapy, and refer to specialists when underlying pathology is identified or conservative measures are ineffective.
尿失禁,即尿液不受控制地流失,是一种常见的健康问题,可能会降低生活质量。10%至 20%的女性和高达 77%居住在养老院的女性患有尿失禁,但只有 25%寻求或接受治疗。
本文综述了女性尿失禁的评估和治疗选择。初始评估应侧重于了解尿失禁对生活质量的影响、患者对治疗的目标和偏好、以前治疗的结果以及并存疾病的存在,如需要转诊的晚期盆腔器官脱垂。需要排除感染和血尿。在没有尿路感染或与尿失禁相关的严重潜在病理(如癌症或严重神经疾病)的情况下,临床医生应开始对患者进行无需监督的骨盆肌肉锻炼和生活方式调整,以减轻其症状。这些建议可以包括减肥、充足的水分摄入、避免过度饮水和规律的排尿间隔,以减少急迫性尿失禁发作。在无需广泛评估的情况下,可以开始使用急迫性尿失禁药物,并及时重新评估症状。急迫性尿失禁的专科治疗包括肉毒杆菌毒素 A 和经皮或植入神经调节剂。压力性尿失禁手术,即尿道中段吊带术,可使 48%至 90%的女性症状得到改善,且网片并发症发生率较低(<5%)。
尿失禁在女性中很常见,尽管有许多有效的治疗方法,但很少有女性寻求治疗。临床医生应优先考虑尿失禁的检测,确定和治疗可改变的因素,将患者的偏好纳入评估和治疗中,启动保守和药物治疗,并在发现潜在病理或保守措施无效时转介给专家。