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在一名肝素诱导的血小板减少症患者中使用全身性比伐卢定联合导管直接溶栓治疗:一例病例报告。

Use of systemic bivalirudin with catheter-directed thrombolysis in a patient with heparin-induced thrombocytopenia: A case report.

作者信息

Badreldin Hisham A, Rimsans Jessica, Connors Jean M, Wiviott Stephen D

机构信息

Division of Pharmacy Services, Brigham and Women's Hospital, Boston, Massachusetts.

King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

出版信息

Catheter Cardiovasc Interv. 2018 Feb 15;91(3):E17-E20. doi: 10.1002/ccd.27368. Epub 2017 Oct 25.

Abstract

In patients with submassive pulmonary embolism, the use of catheter-directed thrombolysis (CDT), using low-dose alteplase is associated with improvement in overall hemodynamics. The data for use of CDT in patients with heparin-induced thrombocytopenia are limited. We report a case of CDT in a patient with HIT using bivalirudin anticoagulation. Data of the use of bivalirudin and argatroban for systemic anticoagulation with CDT are limited.

摘要

在次大面积肺栓塞患者中,使用低剂量阿替普酶进行导管定向溶栓(CDT)与整体血流动力学改善相关。肝素诱导的血小板减少症患者使用CDT的数据有限。我们报告了1例使用比伐卢定抗凝的肝素诱导的血小板减少症患者进行CDT的病例。比伐卢定和阿加曲班用于CDT全身抗凝的数据有限。

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